Source: Health Products Regulatory Authority (ZA) Revision Year: 2017 Publisher: PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191
TREPILINE 10 (tablets).
TREPILINE 25 (tablets).
| Pharmaceutical Form |
|---|
|
TREPILINE 10: Pale blue, round, shallow, biconvex, film-coated tablets, plain on both sides. TREPILINE 25: Yellow, round, shallow, biconvex, film-coated tablet, plain on both sides. |
Each tablet contains 10 mg amitriptyline hydrochloride.
Excipients: Colloidal silicon dioxide, disodium edetate, indigo carmine aluminium lake 73015, lactose monohydrate, macrogol, magnesium stearate, polyvinyl alcohol, starch (maize), starch (pregelatinised), sunset yellow FCF aluminium lake 15985, talc, titanium dioxide 77891, quinolene yellow aluminium lake 47005.
Contains sugar: Lactose monohydrate 60 mg.
Each tablet contains 25 mg amitriptyline hydrochloride.
Excipients: Colloidal silicon dioxide, disodium edetate, indigo carmine aluminium lake 73015, iron oxide yellow 77492, lactose monohydrate, macrogol, magnesium stearate, polyvinyl alcohol, starch (maize), starch (pregelatinised), sunset yellow FCF aluminium lake 15985, talc, titanium dioxide 77891, quinolene yellow aluminium lake 47005.
Contains sugar: Lactose monohydrate 40 mg.
| Active Ingredient | Description | |
|---|---|---|
| Amitriptyline |
Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity. |
| List of Excipients |
|---|
|
Colloidal silicon dioxide |
TREPILINE 10: Packs of 100 and 500 tablets in white polypropylene securitainers together with a foam insert/rayon and professional information which is sealed with white, low density polyethylene securitainer caps.
Packs of 28 tablets into metallised patient ready packs which are sealed with lay-flat zips after filling and packed into polyethylene bags.
TREPILINE 25: Packs of 100 and 500 tablets in white polypropylene securitainers together with a foam insert/rayon and professional information which is sealed with white low density polyethylene securitainer caps.
Packs of 28 and 84 tablets into metallised patient ready packs which are sealed with lay-flat zips after filling and packed into polyethylene bags.
Not all packs and pack sizes are necessarily marketed.
PHARMACARE LIMITED, Healthcare Park, Woodlands Drive, Woodmead 2191
TREPILINE 10: J/1.2/219
TREPILINE 25: J/1.2/220
| Drug | Countries | |
|---|---|---|
| TREPILINE | South Africa |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
