Amitriptyline
Also known as: Amitriptyline hydrochloride
Active ingredient description
Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Amitriptyline is the active ingredient of these drugs:
South Africa
Germany South Africa
Germany
Cyprus New Zealand
Brazil Tunisia
Ecuador
Ireland
Spain
Canada France United States
Australia Hong Kong
Australia
France Italy Turkey
South Africa
Austria Estonia South Africa
Germany
South Africa
Hong Kong
Hong Kong Singapore
Finland
Spain
South Africa
Amitriptyline is also found within below combination drugs:
ADEPSIQUE , KLOTRIPTYL , LIMBITROL , NOBRITOL , PERTRIPTYL
Structural formula
Chemical formula: C₂₀H₂₃N
Molecular mass: 277.403 g/mol