Amitriptyline
Also known as: Amitriptyline hydrochloride
Active ingredient description
Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Medicines
Amitriptyline is the active ingredient of these drugs:
South Africa
Germany South Africa
Germany
Cyprus New Zealand
Brazil Tunisia
Ireland
Spain
Canada France United States
Australia Hong Kong
Australia
France Italy
South Africa
Austria
Germany
Hong Kong
Hong Kong Singapore
Finland
Spain
Amitriptyline is also found within below combination drugs:
KLOTRIPTYL , LIMBITROL , NOBRITOL , PERTRIPTYL
Product monographs
Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):
Structural formula
Unique ingredient identifier (UNII)
1806D8D52K - AMITRIPTYLINE
CAS registry number
50-48-6 - amitriptyline
549-18-8 - Amitriptyline hydrochloride
SNOMED-CT
372726002 - Amitriptyline (substance)