Amitriptyline

Also known as: Amitriptyline hydrochloride

Active ingredient description

Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
N06AA09
Amitriptyline
N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AA Non-selective monoamine reuptake inhibitors
Discover more medicines within N06AA09

Medicines

Amitriptyline is the active ingredient of these drugs:

Drug
Countries
AMINEURIN

Germany

AMIOXID-NEURAX

Germany

AMIROL

Cyprus

AMYTRIL

Brazil Tunisia

ASTILIN

Ireland

DEPRELIO

Spain

ELAVIL

Canada France United States

ENDEP

Australia Hong Kong

ENTRIP

Australia

LAROXYL

France

SAROTEN

Austria

SYNEUDON

Germany

TRIPSYL

Hong Kong

TRIPTA

Hong Kong Singapore

TRYPTIZOL

Spain

Amitriptyline is also found within below combination drugs:

LIMBITROL , NOBRITOL

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
AMITRIPTYLINE Film-coated tablet
Summary of product characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

1806D8D52K - AMITRIPTYLINE

CAS registry number

50-48-6 - amitriptyline

549-18-8 - Amitriptyline hydrochloride

SNOMED-CT

372726002 - Amitriptyline (substance)

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