Amitriptyline Other names: Amitriptyline hydrochloride

Chemical formula: C₂₀H₂₃N Molecular mass: 277.403 g/mol PubChem compound: 2160

Active ingredient description

Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group		Classification
N06AA09	Amitriptyline	N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AA Non-selective monoamine reuptake inhibitors
Discover more medicines within N06AA09

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document	Type	Information Source
AMITRIPTYLINE Film-coated tablet	MPI, EU: SmPC	Medicines & Healthcare Products Regulatory Agency (GB)

Medicines

Amitriptyline is an active ingredient of these brands:

Albania (AL)

AMYZOL as AMITRIPTYLINE HYDROCHLORIDE

Australia (AU)

ENDEP as AMITRIPTYLINE HYDROCHLORIDE
ENTRIP as AMITRIPTYLINE HYDROCHLORIDE

Austria (AT)

SAROTEN as AMITRIPTYLINE HYDROCHLORIDE

Brazil (BR)

AMYTRIL as AMITRIPTYLINE HYDROCHLORIDE
(combination) LIMBITROL as AMITRIPTYLINE HYDROCHLORIDE

Canada (CA)

ELAVIL as AMITRIPTYLINE HYDROCHLORIDE

Cyprus (CY)

AMIROL as AMITRIPTYLINE HYDROCHLORIDE

Ecuador (EC)

ANAPSIQUE

Estonia (EE)

SAROTEN as AMITRIPTYLINE HYDROCHLORIDE

Finland (FI)

TRIPTYL as AMITRIPTYLINE HYDROCHLORIDE
(combination) KLOTRIPTYL as AMITRIPTYLINE HYDROCHLORIDE
(combination) LIMBITROL as AMITRIPTYLINE HYDROCHLORIDE
(combination) PERTRIPTYL as AMITRIPTYLINE HYDROCHLORIDE

France (FR)

ELAVIL as AMITRIPTYLINE HYDROCHLORIDE
LAROXYL as AMITRIPTYLINE HYDROCHLORIDE

Germany (DE)

AMINEURIN as AMITRIPTYLINE HYDROCHLORIDE
AMIOXID-NEURAX as Amitriptyline dihydrate
SYNEUDON as AMITRIPTYLINE HYDROCHLORIDE

Hong Kong (HK)

ENDEP as AMITRIPTYLINE HYDROCHLORIDE
TRIPSYL as AMITRIPTYLINE HYDROCHLORIDE
TRIPTA as AMITRIPTYLINE HYDROCHLORIDE

Ireland (IE)

ASTILIN as AMITRIPTYLINE HYDROCHLORIDE

Israel (IL)

ELATROL as AMITRIPTYLINE HYDROCHLORIDE
ELATROLET as AMITRIPTYLINE HYDROCHLORIDE

Italy (IT)

LAROXYL as AMITRIPTYLINE HYDROCHLORIDE

Japan (JP)

TRYPTANOL as AMITRIPTYLINE HYDROCHLORIDE

Malta (MT)

AMIROL as AMITRIPTYLINE HYDROCHLORIDE

Mexico (MX)

(combination) ADEPSIQUE as AMITRIPTYLINE HYDROCHLORIDE

New Zealand (NZ)

AMIROL as AMITRIPTYLINE HYDROCHLORIDE

Nigeria (NG)

MEDITRILINE as AMITRIPTYLINE HYDROCHLORIDE

Singapore (SG)

TRIPTA as AMITRIPTYLINE HYDROCHLORIDE

South Africa (ZA)

AMDERIP as AMITRIPTYLINE HYDROCHLORIDE
AMINEURIN as AMITRIPTYLINE HYDROCHLORIDE
NORILINE as AMITRIPTYLINE HYDROCHLORIDE
SAROTEN as AMITRIPTYLINE HYDROCHLORIDE
TREPILINE as AMITRIPTYLINE HYDROCHLORIDE
VEIKIRIN as AMITRIPTYLINE HYDROCHLORIDE
(combination) LIMBITROL as AMITRIPTYLINE HYDROCHLORIDE

Spain (ES)

DEPRELIO
TRYPTIZOL as AMITRIPTYLINE HYDROCHLORIDE
(combination) NOBRITOL as AMITRIPTYLINE HYDROCHLORIDE

Tunisia (TN)

AMYTRIL as AMITRIPTYLINE HYDROCHLORIDE

Turkey (TR)

LAROXYL as AMITRIPTYLINE HYDROCHLORIDE

United States (US)

ELAVIL as AMITRIPTYLINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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