Amitriptyline

Also known as: Amitriptyline hydrochloride

Active ingredient description

Amitriptyline is a tricyclic antidepressant and an analgesic. It prevents the re-uptake, and hence the inactivation of noradrenaline and serotonin at nerve terminals. Reuptake prevention of these monoamine neurotransmitters potentiate their action in the brain. This appears to be associated with the antidepressant activity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Amitriptyline
N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AA Non-selective monoamine reuptake inhibitors
Discover more medicines within N06AA09

Medicines

Amitriptyline is the active ingredient of these drugs:

Drug
Countries

South Africa

Germany South Africa

Germany

Cyprus New Zealand

Brazil Tunisia

Ireland

Spain

Canada France United States

Australia Hong Kong

Australia

France Italy

South Africa

Austria

Germany

Hong Kong

Hong Kong Singapore

Finland

Spain

Amitriptyline is also found within below combination drugs:

KLOTRIPTYL , LIMBITROL , NOBRITOL , PERTRIPTYL

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

1806D8D52K - AMITRIPTYLINE

CAS registry number

50-48-6 - amitriptyline

549-18-8 - Amitriptyline hydrochloride

SNOMED-CT

372726002 - Amitriptyline (substance)