Active ingredients: Brimonidine
Alphagan 0.2% w/v (2 mg/ml) eye drops, solution.
Eye drops, solution.
Clear, greenish-yellow to light greenish-yellow solution.
One ml solution contains 2.0 mg brimonidine tartrate, equivalent to 1.3 mg of brimonidine.
Excipient(s): Contains benzalkonium chloride 0.05 mg/ml. For a full list of excipients, see section 6.1.
Brimonidine is an alpha2-adrenergic receptor agonist that is 1000-fold more selective for the alpha2-adrenoceptor than the alpha1-adrenoreceptor. This selectivity results in no mydriasis and the absence of vasoconstriction in microvessels associated with human retinal xenografts.
Benzalkonium chloride
Poly(vinyl alcohol)
Sodium chloride
Sodium citrate
Citric acid monohydrate
Purified water
Hydrochloric acid (for pH-adjustment) or
Sodium hydroxide (for pH-adjustment)
White low density polyethylene dropper bottles with a 35 microlitre tip. The cap is either a conventional polystyrene screw cap or a Compliance Cap (C-Cap).
2.5 ml, 5 ml and 10 ml bottles in packs of 1, 3 or 6.
Not all pack sizes may be marketed.
Allergan Ltd, 1st Floor Marlow International, The Parkway, Marlow, Buckinghamshire SL7 1YL, UK
PL 00426/0088
Date of first authorisation: 18 March 1997
Date of last renewal: 17 September 2006