Chemical formula: C₁₁H₁₀BrN₅ Molecular mass: 292.135 g/mol PubChem compound: 2435
Brimonidine is an alpha2-adrenergic receptor agonist that is 1000-fold more selective for the alpha2-adrenoceptor than the alpha1-adrenoreceptor. This selectivity results in no mydriasis and the absence of vasoconstriction in microvessels associated with human retinal xenografts.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D11AX21 | D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AX Other dermatologicals | |
| S01EA05 | Brimonidine | S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EA Sympathomimetics in glaucoma therapy |
| S01GA07 | S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GA Sympathomimetics used as decongestants | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| MIRVASO Gel | European Medicines Agency (EU) | MPI, EU: SmPC | |
| ALPHAGAN Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ALPHAGAN P Ophthalmic solution / drops | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Brimonidine is an active ingredient of these brands:
United States (US)Australia (AU)Austria (AT)Brazil (BR)
Canada (CA)Croatia (HR)Cyprus (CY)Ecuador (EC)
Estonia (EE)Finland (FI)France (FR)Hong Kong (HK)Ireland (IE)Israel (IL)Italy (IT)Japan (JP)Lithuania (LT)Malta (MT)Mexico (MX)Netherlands (NL)New Zealand (NZ)Nigeria (NG)Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)
Spain (ES)Tunisia (TN)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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