Brimonidine

Chemical formula: C₁₁H₁₀BrN₅  Molecular mass: 292.135 g/mol  PubChem compound: 2435

Active ingredient description

Brimonidine is an alpha2-adrenergic receptor agonist that is 1000-fold more selective for the alpha2-adrenoceptor than the alpha1-adrenoreceptor. This selectivity results in no mydriasis and the absence of vasoconstriction in microvessels associated with human retinal xenografts.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D11AX21 D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AX Other dermatologicals
Discover more medicines within D11AX21
S01EA05 Brimonidine S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EA Sympathomimetics in glaucoma therapy
Discover more medicines within S01EA05
S01GA07 S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GA Sympathomimetics used as decongestants
Discover more medicines within S01GA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ALPHAGAN Eye drops, solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MIRVASO Gel European Medicines Agency (EU) MPI, EU: SmPC
ALPHAGAN P Ophthalmic solution / drops FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 59803-98-4
DrugBank Drug: DB00484
KEGG Drug: D07540
PubChem Compound: 2435
RxNorm Ingredient: 134615
SNOMED-CT Concept: 372547000
Brimonidine (substance)
UNII Identifier: E6GNX3HHTE
BRIMONIDINE

Medicines

Brimonidine is an active ingredient of these brands:

United States (US)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • LUMIFY as BRIMONIDINE TARTRATE
  • MIRVASO as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Australia (AU)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • ENIDIN as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Austria (AT)

Brazil (BR)

  • ALPHABRIN as BRIMONIDINE TARTRATE
  • ALPHAGAN as BRIMONIDINE TARTRATE
  • GLAUB as BRIMONIDINE TARTRATE

  • (combination) BRITENS as BRIMONIDINE TARTRATE
  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE
  • (combination) TINODIN as BRIMONIDINE TARTRATE
  • (combination) TRIPLENEX as BRIMONIDINE TARTRATE
  • (combination) VISONEO as BRIMONIDINE TARTRATE

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

  • AGGLAD OFTENO as BRIMONIDINE TARTRATE
  • ALPHAGAN as BRIMONIDINE TARTRATE
  • BRIMOF as BRIMONIDINE TARTRATE

  • (combination) BRIMOLOL as BRIMONIDINE TARTRATE
  • (combination) BRIMOTIM as BRIMONIDINE TARTRATE
  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) GLAUCOMAX as BRIMONIDINE TARTRATE
  • (combination) KRYTANTEK as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE
  • (combination) TIBRODINA as BRIMONIDINE TARTRATE
  • (combination) TRIPLIGAN as BRIMONIDINE TARTRATE
  • (combination) XEGREX as BRIMONIDINE TARTRATE

Estonia (EE)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • MIRVASO as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Finland (FI)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • MIRVASO as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

France (FR)

Hong Kong (HK)

Ireland (IE)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • MIRVASO as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Israel (IL)

  • ALPHAGAN as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Italy (IT)

Japan (JP)

  • AIPHAGAN as BRIMONIDINE TARTRATE

  • (combination) AILAMIDE as BRIMONIDINE TARTRATE
  • (combination) GLA-ALPHA as BRIMONIDINE TARTRATE

Lithuania (LT)

Malta (MT)

Mexico (MX)

  • ALPHAGAN as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Netherlands (NL)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • MIRVASO as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

  • BRIMONAL as BRIMONIDINE TARTRATE

  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

  • ALPHAGAN as BRIMONIDINE TARTRATE
  • BREMON as BRIMONIDINE TARTRATE
  • BRIMODER as BRIMONIDINE TARTRATE
  • BRIMOGUT as BRIMONIDINE TARTRATE
  • BRIMOLIX as BRIMONIDINE TARTRATE
  • BRIOP as BRIMONIDINE TARTRATE
  • GLOGER as BRIMONIDINE TARTRATE
  • RIMONAL as BRIMONIDINE TARTRATE

  • (combination) BRIMOTIM as BRIMONIDINE TARTRATE
  • (combination) COMBIGAN as BRIMONIDINE TARTRATE
  • (combination) RIMOSOPT as BRIMONIDINE TARTRATE
  • (combination) SIMBRINZA as BRIMONIDINE TARTRATE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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