Brimonidine

Chemical formula: C₁₁H₁₀BrN₅  Molecular mass: 292.135 g/mol  PubChem compound: 2435

Therapeutic indications

Brimonidine is indicated for:

Elevated intraocular pressure (IOP) in patients with open angle glaucoma or ocular hypertension

Population group: only adults (18 years old or older)

  • As monotherapy in patients in whom topical beta-blocker therapy is contraindicated.
  • As adjunctive therapy to other intraocular pressure lowering medications when the target IOP is not achieved with a single agent.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Facial erythema of rosacea

Population group: only adults (18 years old or older)

Brimonidine is indicated for the symptomatic treatment of facial erythema of rosacea in adult patients.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Brimonidine is contraindicated in the following cases:

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors (MAOIs)

Antidepressants affecting noradrenergic transmission

at least one of

Noradrenaline re-uptake inhibitors (NRIs)
Mianserin

Lactation

Lactation

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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