Active ingredients: Aprotinin
Aprotinin 10,000 KIU/ml Injection BP.
Solution for Injection.
Each 50ml vial contains aprotinin solution corresponding to 500,000 Kallikrein Inactivator Units, KIU (= 277.8 European Pharmacopoeia, E.P. units) aprotinin in 0.9% sodium chloride solution.
For a full list of excipients, see section 6.1.
Aprotinin is a broad spectrum protease inhibitor which has antifibrinolytic properties. By forming reversible stoichiometric enzyme-inhibitor complexes, aprotinin acts as an inhibitor of human trypsin, plasmin, plasma kallikrein and tissue kallikrein, thus inhibiting fibrinolysis.
Water for injections
Clear glass vials of 50ml.
Nordic Group B.V., Siriusdreef 22, 2132 WT Hoofddorp, the Netherlands
1st April 2003