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Aprotinin

Description

Aprotinin is a broad spectrum protease inhibitor which has antifibrinolytic properties. By forming reversible stoichiometric enzyme-inhibitor complexes, aprotinin acts as an inhibitor of human trypsin, plasmin, plasma kallikrein and tissue kallikrein, thus inhibiting fibrinolysis.

ATC Classification

Code
Title
Category
B02AB01
Aprotinin
B Blood and blood forming organs → B02 Antihemorrhagics → B02A Antifibrinolytics → B02AB Proteinase inhibitors

Trade names

Trade name
Countries

Austria Singapore

Trade names (in combination): ARTISS TISSEEL

Product Monographs

Monograph
Type
Country
APROTININ Solution for injection
MPI, EU: SmPC
UK