Aprotinin

Chemical formula: C₂₈₄H₄₃₂N₈₄O₇₉S₇  Molecular mass: 6,510.051 g/mol  PubChem compound: 22833874

Active ingredient description

Aprotinin is a broad spectrum protease inhibitor which has antifibrinolytic properties. By forming reversible stoichiometric enzyme-inhibitor complexes, aprotinin acts as an inhibitor of human trypsin, plasmin, plasma kallikrein and tissue kallikrein, thus inhibiting fibrinolysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B02AB01 Aprotinin B Blood and blood forming organs → B02 Antihemorrhagics → B02A Antifibrinolytics → B02AB Proteinase inhibitors
Discover more medicines within B02AB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
APROTININ Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

External identifiers

CAS Substance: 9004-04-0
CAS Substance: 9087-70-1
DrugBank Drug: DB06692
KEGG Drug: D02971
PubChem Compound: 22833874
RxNorm Ingredient: 1056
SNOMED-CT Concept: 386961008
Aprotinin (substance)
UNII Identifier: 04XPW8C0FL
APROTININ

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.