Aprotinin

Active ingredient description

Aprotinin is a broad spectrum protease inhibitor which has antifibrinolytic properties. By forming reversible stoichiometric enzyme-inhibitor complexes, aprotinin acts as an inhibitor of human trypsin, plasmin, plasma kallikrein and tissue kallikrein, thus inhibiting fibrinolysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Aprotinin
B Blood and blood forming organs → B02 Antihemorrhagics → B02A Antifibrinolytics → B02AB Proteinase inhibitors
Discover more medicines within B02AB01

Medicines

Aprotinin is the active ingredient of these drugs:

Drug
Countries

Austria France Ireland Singapore

Aprotinin is also found within below combination drugs:

ARTISS , BERIPLAST-P , TACHOCOMB , TISSEEL

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of product characteristics (SPC)
UK

Unique ingredient identifier (UNII)

04XPW8C0FL - APROTININ

CAS registry number

9004-04-0 - Trypsin inhibitor, pancreatic basic

9087-70-1 - aprotinin

SNOMED-CT

386961008 - Aprotinin (substance)