Aprotinin is a broad spectrum protease inhibitor which has antifibrinolytic properties. By forming reversible stoichiometric enzyme-inhibitor complexes, aprotinin acts as an inhibitor of human trypsin, plasmin, plasma kallikrein and tissue kallikrein, thus inhibiting fibrinolysis.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Aprotinin is the active ingredient of these drugs:
Austria France Ireland Singapore
Aprotinin is also found within below combination drugs:
ARTISS , BERIPLAST-P , TACHOCOMB , TISSEEL
Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):