Therapeutic indications

Aprotinin is indicated for:

High risk of major blood loss undergoing cardiovascular surgery

Population group: both men and women, only adults (18 years old or older)

Aprotinin is indicated for prophylactic use to reduce blood loss and blood transfusion in adult patients who are at high risk of major blood loss undergoing isolated cardiopulmonary bypass graft surgery (i.e. coronary artery bypass graft surgery that is not combined with other cardiovascular surgery).

Aprotinin should only be used after careful consideration of the benefits and risks, and the consideration that alternative treatments are available.

For this indication, competent medicine agencies globally authorize below treatments (click for details):


Aprotinin is contraindicated in the following cases:

Hypersensitivity to aprotinin

Aprotinin allergy

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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