Active ingredients: Bifonazole Clotrimazole
Canesten Bifonazole Once Daily 1% w/w Cream.
Canesten Bifonazole Once Daily Athlete’s Foot 1% w/w Cream.
A white cream.
The cream contains 1% w/w bifonazole.
Excipient with known effect: cetostearyl alcohol.
For excipients see section 6.1.
Bifonazole is an imidazole derivative with a broad antimycotic spectrum, which includes dermatophytes, yeasts, moulds and other fungi such as Malassezia furfur. It is also effective against Corynebacterium minutissimum.
Clotrimazole acts against fungi by inhibiting ergosterol synthesis. Inhibition of ergosterol synthesis leads to structural and functional impairment of the fungal cytoplasmic membrane. Clotrimazole has a broad antimycotic spectrum of action in vitro and in vivo, which includes dermatophytes, yeasts, moulds, etc.
Sorbitan stearate
Polysorbate 60
Cetyl palmitate
Cetostearyl alcohol
2-Octyldodecanol
Benzyl alcohol
Purified Water
Aluminium tubes containing 15g, 20g, 25g or 30g of cream.
Bayer plc, 400 South Oak Way, Reading, RG2 6AD
PL 00010/0508
28/11/2007