Active ingredients: Levobupivacaine
Chirocaine 5 mg/ml solution for injection/concentrate for solution for infusion.
Solution for injection/concentrate for solution for infusion.
Clear colourless solution.
One ml contains 5 mg levobupivacaine as levobupivacaine hydrochloride.
Each ampoule contains 50 mg in 10 ml.
Excipients with known effect: 3.5 mg/ml of sodium per ampoule.
For the full list of excipients, see section 6.1.
Levobupivacaine is a long acting local anaesthetic and analgesic. It blocks nerve conduction in sensory and motor nerves largely by interacting with voltage sensitive sodium channels on the cell membrane, but also potassium and calcium channels are blocked. In addition, levobupivacaine interferes with impulse transmission and conduction in other tissues where effects on the cardiovascular and central nervous systems are most important for the occurrence of clinical adverse reactions.
Sodium chloride
Sodium hydroxide
Hydrochloric acid
Water for injections
Chirocaine is available in two presentations:
Not all pack sizes may be marketed.
AbbVie Ltd., Maidenhead, SL6 4UB, UK
PL41042/0006
Date of first authorisation: 06th January 2000
Date of last renewal: 18th December 2013