Chemical formula: C₁₈H₂₈N₂O  Molecular mass: 288.428 g/mol  PubChem compound: 92253

Active ingredient description

Levobupivacaine is a long acting local anaesthetic and analgesic. It blocks nerve conduction in sensory and motor nerves largely by interacting with voltage sensitive sodium channels on the cell membrane, but also potassium and calcium channels are blocked. In addition, levobupivacaine interferes with impulse transmission and conduction in other tissues where effects on the cardiovascular and central nervous systems are most important for the occurrence of clinical adverse reactions.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N01BB10 Levobupivacaine N Nervous system → N01 Anesthetics → N01B Anesthetics, local → N01BB Amides
Discover more medicines within N01BB10

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CHIROCAINE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 27262-47-1
DrugBank Drug: DB01002
KEGG Drug: D08116
PubChem Compound: 92253
RxNorm Ingredient: 259453
SNOMED-CT Concept: 334207003
Levobupivacaine (substance)
SNOMED-CT Concept: 387011006
Levobupivacaine (substance)
UNII Identifier: A5H73K9U3W
UNII Identifier: J998RDZ51I


Levobupivacaine is an active ingredient of these brands:

Brazil (BR)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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