Levobupivacaine
Active ingredient description
Levobupivacaine is a long acting local anaesthetic and analgesic. It blocks nerve conduction in sensory and motor nerves largely by interacting with voltage sensitive sodium channels on the cell membrane, but also potassium and calcium channels are blocked. In addition, levobupivacaine interferes with impulse transmission and conduction in other tissues where effects on the cardiovascular and central nervous systems are most important for the occurrence of clinical adverse reactions.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Levobupivacaine is the active ingredient of these drugs:
Levobupivacaine is also found within below combination drugs:
Structural formula
Chemical formula: C₁₈H₂₈N₂O
Molecular mass: 288.428 g/mol
External identifiers
- CAS Substance: 27262-47-1
- DrugBank Drug: DB01002
- KEGG Drug: D08116
- PubChem Compound: 92253
- RxNorm Ingredient: 259453
- SNOMED-CT Concept: 334207003
- Levobupivacaine (substance)
- SNOMED-CT Concept: 387011006
- Levobupivacaine (substance)
- UNII Identifier: A5H73K9U3W
- LEVOBUPIVACAINE
- UNII Identifier: J998RDZ51I
- LEVOBUPIVACAINE HYDROCHLORIDE