Active ingredients: Chlorambucil
Chlorambucil 2 mg tablets.
Brown, round, biconvex, film-coated tablets, one side engraved with “L” and the other side engraved ‘GX EG 3’.
Each tablet contains 2 mg of the active ingredient chlorambucil.
Excipient(s) with known effect: Each tablet also contains 67.65 mg of lactose.
For the full list of excipients, see section 6.1.
Chlorambucil is an aromatic nitrogen mustard derivative which acts as a bifunctional alkylating agent. In addition to interference with DNA replication, chlorambucil induces cellular apoptosis via the accumulation of cytosolic p53 and subsequent activation of an apoptosis promoter.
Microcrystalline cellulose (E460)
Colloidal anhydrous silica
Stearic acid (E570)
Tablet Film Coating:
Titanium dioxide (E171)
Synthetic yellow iron oxide (E172)
Synthetic red iron oxide (E172)
Chlorambucil tablets are brown, round, biconvex, film-coated tablets, one side engraved with ‘L’ and the other side engraved ‘GX EG3’, supplied in amber glass bottles with a child resistant closure containing 25 tablets.
Aspen Pharma Trading Limited, 3016 Lake Drive, Citywest Business Campus, Dublin 24, Ireland
22 June 2006