DERMOVATE Scalp application

Active ingredients: Clobetasol propionate

Product name and form

Dermovate Scalp Application.

Pharmaceutical Form

Scalp application.

Qualitative and quantitative composition

Each 1 g contains 0.5 mg of clobetasol propionate (0.05% w/w).

Active Ingredient

Clobetasol propionate, like other topical corticosteroids, has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.

List of Excipients

Isopropyl Alcohol
Sodium Hydroxide
Purified Water

Pack sizes and marketing

White High Density Polyethylene (HDPE) container with a white low density polyethylene (LDPE) nozzle and a white HDPE screw cap.

Pack size: 25ml, 30ml, 100ml.

Not all pack sizes may be marketed.

Marketing authorization holder

Glaxo Wellcome UK Ltd trading as Glaxo Laboratories and/or GlaxoSmithKline UK, 980 Great West Road, Brentford, Middlesex, TW8 9GS

Marketing authorization dates and numbers

PL 10949/0046

Date of first authorisation: 01 April 1993
Date of last renewal: 24 February 2010


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