Active ingredients: Acetazolamide
Diamox SR 250mg Prolonged-release Capsules.
Orange spherical pellets contained in a size ‘1’ capsule with clear body and opaque orange cap. ‘GS 250’ is printed on the orange cap in black text.
Each capsule contains 250 mg acetazolamide.
Excipient(s): For a full list of excipients, see section 6.1.
Acetazolamide is an enzyme inhibitor which acts specifically on carbonic anhydrase. By inhibiting the reaction catalysed by this enzyme in the renal tubules, acetazolamide increases the excretion of bicarbonate and of cations, chiefly sodium and potassium, and so promotes alkaline diuresis. By inhibiting carbonic anhydrase in the eye acetazolamide decreases intra-ocular pressure and is therefore useful in the treatment of glaucoma.
Film coated Pellets:
Microcrystalline Cellulose, sodium Lauryl sulphate, purified water, ethylcellulose, Hydroxypropylmethyl cellulose (E464), mineral oil light and Pigment Blend PB-230005 Orange [hydroxyl propyl cellulose, titanium dioxide and FD&C Yellow #6/Sunset yellow FCF aluminium lake (15–18% grade), Talc and FD&C Yellow #6/Sunset yellow FCF aluminium lake (38–42% grade)].
Gelatine, titanium dioxide (E171), yellow iron oxide (E172) erythrosine (E127).
Blister Packs: 28 and 30 Capsules/ Pack
Opaque UPVC/PVDC blister Pack heat sealed with aluminium foil backing in an outer carton
Not all pack sizes may be marketed.
Mercury Pharmaceuticals Ltd., Capital House, 85 King William Street, London EC4N 7BL, UK
22 June 2004