Chemical formula: C₄H₆N₄O₃S₂  Molecular mass: 222.245 g/mol  PubChem compound: 1986

Active ingredient description

Acetazolamide is an enzyme inhibitor which acts specifically on carbonic anhydrase. By inhibiting the reaction catalysed by this enzyme in the renal tubules, acetazolamide increases the excretion of bicarbonate and of cations, chiefly sodium and potassium, and so promotes alkaline diuresis. By inhibiting carbonic anhydrase in the eye acetazolamide decreases intra-ocular pressure and is therefore useful in the treatment of glaucoma.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
S01EC01 Acetazolamide S Sensory organs → S01 Ophthalmologicals → S01E Antiglaucoma preparations and miotics → S01EC Carbonic anhydrase inhibitors
Discover more medicines within S01EC01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
DIAMOX Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DIAMOX SR Capsule Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
DIAMOX Sodium Powder for solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 59-66-5
DrugBank Drug: DB00819
KEGG Drug: D00218
PubChem Compound: 1986
RxNorm Ingredient: 167
SNOMED-CT Concept: 372709008
Acetazolamide (substance)
UNII Identifier: O3FX965V0I


Acetazolamide is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Croatia (HR)

Ecuador (EC)

France (FR)

Germany (DE)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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