Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Baxter Healthcare Ltd., Caxton Way, Thetford, Norfolk, IP24 3SE, United Kingdom
Pharmacotherapeutic group: "Other IV Solution Additives"
ATC code: B05BA03
The pharmacodynamic properties of this solution are those of glucose, which forms the principal source of energy in cellular metabolism. Glucose 5% is given as a source of carbohydrate in parenteral nutrition. The Glucose 5% solution provides a caloric intake of 200 kcal/l. Furthermore, this glucose solution for infusion allows hydric supplementation without ionic supplementation.
Glucose 5% is a isosmotic solution, with an approximate osmolarity of 278 mOsm/l.
The pharmacodynamics of the additive will depend on the nature of the drug used.
Glucose is metabolized via pyruvic or lactic acid to carbon dioxide and water with the release of energy.
The pharmacokinetics of the additive will depend on the nature of the drug used.
The safety of glucose in animals is not relevant in view of its presence as a normal component in animal and human plasma.
The safety of the additive should be considered separately.
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