HYDREX Cutaneous solution Ref.[28097] Active ingredients: Chlorhexidine

Source: Health Products Regulatory Authority (IE)  Revision Year: 2019  Publisher: Ecolab Deutschland GmbH, Ecolab-Allee 1, D-40789 Monheim am Rhein, Germany

5.1. Pharmacodynamic properties

ATC Code: D08AC02

Chlorhexidine is a bisbiguanide disinfectant which is active against a wide range of Gram-positive and Gram-negative vegetative bacteria. It is also active against some viruses and some fungi. It is most active at neutral or slightly acid pH.

5.2. Pharmacokinetic properties

Percutaneous absorption of chlorhexidine gluconate is negligible and leads to clinically insignificant plasma concentrations.

5.3. Preclinical safety data

Preclinical data reveal no special hazard for humans based on conventional studies of repeated dose toxicity, carcinogenic potential and toxicity to reproduction.

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