Chlorhexidine Other names: Decanoylacetaldehyde Sodium Sulfide
Chemical formula: C₂₂H₃₀Cl₂N₁₀ Molecular mass: 505.447 g/mol PubChem compound: 9552079
Active ingredient description
Chlorhexidine is an antimicrobial agent, active against a broad spectrum of Gram-positive and Gram-negative organisms, yeasts, fungi, opportunistic anaerobes and aerobes. Chlorhexidine is mainly a “membrane-acting” agent that destroys the outer membrane of the bacteria. It is inactive on bacterial spores unless the temperatures are high.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| A01AB03 | Chlorhexidine | A Alimentary tract and metabolism → A01 Stomatological preparations → A01A Stomatological preparations → A01AB Antiinfectives and antiseptics for local oral treatment |
| B05CA02 | Chlorhexidine | B Blood and blood forming organs → B05 Blood substitutes and perfusion solutions → B05C Irrigating solutions → B05CA Antiinfectives |
| D08AC02 | Chlorhexidine | D Dermatologicals → D08 Antiseptics and disinfectants → D08A Antiseptics and disinfectants → D08AC Biguanides and amidines |
| D09AA12 | Chlorhexidine | D Dermatologicals → D09 Medicated dressings → D09A Medicated dressings → D09AA Medicated dressings with antiinfectives |
| R02AA05 | Chlorhexidine | R Respiratory system → R02 Throat preparations → R02A Throat preparations → R02AA Antiseptics |
| S01AX09 | Chlorhexidine | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AX Other antiinfectives |
| S02AA09 | Chlorhexidine | S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives |
| S03AA04 | Chlorhexidine | S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| PAROEX Oral rinse | MPI, US: SPL/Old | FDA, National Drug Code (US) | |
| ACRIFLEX Cream | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| CORSODYL ORIGINAL Mouthwash | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Chlorhexidine is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)
Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Japan (JP)
Lithuania (LT)
Malta (MT)
Netherlands (NL)
New Zealand (NZ)
Nigeria (NG)
Poland (PL)
Romania (RO)
Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)
Turkey (TR)
United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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