ATC Group: B05C Irrigating solutions

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of B05C in the ATC hierarchy

Level Code Title
1 B Blood and blood forming organs
2 B05 Blood substitutes and perfusion solutions
3 B05C Irrigating solutions

Group B05C contents

Code Title
B05CA Antiinfectives
B05CB Salt solutions
B05CX Other irrigating solutions

Active ingredients in B05C

Active Ingredient Description

Cetylpyridinium is an antiseptic with activity against both gram positive and gram negative organisms.


Chlorhexidine is an antimicrobial agent, active against a broad spectrum of Gram-positive and Gram-negative organisms, yeasts, fungi, opportunistic anaerobes and aerobes. Chlorhexidine is mainly a “membrane-acting” agent that destroys the outer membrane of the bacteria. It is inactive on bacterial spores unless the temperatures are high.

Ethacridine lactate

Glucose is frequently used in both adults and children to restore blood glucose concentrations in the treatment of hypoglycaemia resulting from insulin excess or from other causes. The metabolism of glucose is an energy source for the body.

Magnesium citrate

Mannitol is a naturally occurring sugar alcohol used clinically primarily for its osmotic diuretic properties.


Neomycin is an aminoglycoside antibiotic and acts by binding to polysomes, inhibiting protein synthesis and generating errors in the transcription of the genetic code.

Sodium bicarbonate

Sodium bicarbonate has antacid properties. Sodium bicarbonate causes neutralisation of gastric acid with the production of carbon dioxide.

Sodium chloride

Sodium chloride is the principle salt involved in maintaining the osmotic tension of blood and tissues. Changes in osmotic tension influence the movement of fluids and diffusion of salts in cellular tissue.

Sodium citrate

Sodium citrate has no relevant pharmacodynamic activity other than that caused by its alkalinity (e.g. its gastric acid neutralising capacity). Sodium citrate is a non-particulate antacid for use by mouth to prior to general anaesthesia for caesarean section.


Taurolidine inhibits the formation of postoperative peritoneal adhesions, and in vitro has been shown to reduce the adherence of micro-organisms to mucosal epithelium. The chemical mode of action of taurolidine via its reactive methylol groups confers greater potency in vivo than indicated by in vitro MIC values, and also appears to preclude susceptibility to resistance mechanisms.

Related product monographs

Title Information Source Document Type  
ACIDEX Oral suspension Health Products Regulatory Authority (IE) MPI, EU: SmPC
NIVEMYCIN Tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
STERETS UNISEPT Cutaneous solution Health Products Regulatory Authority (IE) MPI, EU: SmPC
TAUROLIN Solution for intraperitoneal lavage after dilution or solution for instillation Health Products Regulatory Authority (IE) MPI, EU: SmPC