Chemical formula: C₇H₁₆N₄O₄S₂ Molecular mass: 284.35 g/mol PubChem compound: 29566
Taurolidine inhibits the formation of postoperative peritoneal adhesions, and in vitro has been shown to reduce the adherence of micro-organisms to mucosal epithelium. The chemical mode of action of taurolidine via its reactive methylol groups confers greater potency in vivo than indicated by in vitro MIC values, and also appears to preclude susceptibility to resistance mechanisms.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| B05CA05 | Taurolidine | B Blood and blood forming organs → B05 Blood substitutes and perfusion solutions → B05C Irrigating solutions → B05CA Antiinfectives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| TAUROLIN Solution for intraperitoneal lavage after dilution or solution for instillation | Health Products Regulatory Authority (IE) | MPI, EU: SmPC |
Taurolidine is an active ingredient of these brands:
Austria (AT)Ireland (IE)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
