Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2018 Publisher: Forest Laboratories UK Limited, Whiddon Valley, Barnstaple, North Devon, EX32 8NS, United Kingdom
Simeticone is an anti-flatulent with ATC code A03AX13.
Physiologically the active ingredient is a chemically inert, non-systemic gastric defoaming agent that works by altering the elasticity of interfaces of mucus-embedded bubbles in the gastrointestinal tract.
The gas bubbles are thus broken down or coalesced and in this form gas is more easily eliminated through eructation or passing flatus.
Simeticone is not absorbed from the gastrointestinal tract.
There are no preclinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.
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