LIFYORLI Capsule Ref.[116441] Active ingredients:

Source: FDA, National Drug Code (US)  Revision Year: 2026 

Product description

LIFYORLI (relacorilant) is a glucocorticoid receptor antagonist antineoplastic agent.

Relacorilant chemical names:

  • (R)-(1-(4-fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-trifluoromethyl)(pyridin-2-yl)methanone
  • [(4aR)-1-(4-fluorophenyl)-6-(1-methyl-1H-pyrazole-4-sulfonyl)-1,4,5,6,7,8-hexahydro-4aH-pyrazolo[3,4-g]isoquinolin-4a-yl][4-(trifluoromethyl)pyridin-2-yl]methanone

The molecular formula is C27H22F4N6O3S and the molecular weight is 586.57 g/mol.

The chemical structure of relacorilant is:

Relacorilant is an off-white to light yellow solid that is practically insoluble in aqueous media.

LIFYORLI capsules for oral use are supplied as immediate release, printed, soft gelatin capsules containing 25 mg or 100 mg of relacorilant. Each capsule contains the following excipients: butylated hydroxytoluene, lauroyl polyoxyl-32 glycerides, and propylene glycol caprylate. The capsule shell for the 25 mg strength contains black iron oxide, gelatin, red iron oxide, sorbitol special glycerin blend, titanium dioxide, and yellow iron oxide. The capsule shell for the 100 mg strength contains gelatin, sorbitol special glycerin blend, titanium dioxide, and yellow iron oxide. The printing ink contains ammonium hydroxide, black iron oxide, ethanol, ethyl acetate, isopropyl alcohol, macrogol/polyethylene glycol, polyvinyl acetate phthalate, propylene glycol, and purified water.

Dosage Forms and Strengths

Capsules:

  • 25 mg: opaque dark brown, oval soft gelatin capsules with "CR25" printed in black.
  • 100 mg: opaque yellow, oblong soft gelatin capsules with "CR100" printed in black.
How Supplied

LIFYORLI is available as soft gelatin capsules containing 25 mg or 100 mg of relacorilant.

LIFYORLI 25 mg are opaque dark brown, oval soft gelatin capsules with "CR25" printed in black.

LIFYORLI 100 mg are opaque yellow, oblong soft gelatin capsules with "CR100" printed in black.

LIFYORLI capsules are supplied as follows:

DoseEach Carton ContainsEach Blister Card ContainsNDC
150 mgOne blister card of 3 capsules.One 100 mg capsule, and
Two 25 mg capsules.
NDC 76346-450-01
One blister card of 9 capsules.Three 100 mg capsules, and
Six 25 mg capsules.
NDC 76346-550-03
Three cartons each containing one blister card of 9 capsules.
(27 capsules total).
Three 100 mg capsules, and
Six 25 mg capsules.
NDC 76346-550-09
mgOne blister card of 2 capsules.One 100 mg capsule, and
One 25 mg capsule.
NDC 76346-425-01
One blister card of 6 capsules.Three 100 mg capsules, and
Three 25 mg capsules.
NDC 76346-525-03
Three cartons each containing one blister card of 6 capsules.
(18 capsules total).
Three 100 mg capsules, and
Three 25 mg capsules.
NDC 76346-525-09

Manufactured for: Corcept Therapeutics Incorporated, Redwood City, CA 9406

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