Source: European Medicines Agency (EU) Revision Year: 2025 Publisher: AstraZeneca AB, SE-151 85 Södertälje, Sweden
Lokelma 5 g powder for oral suspension.
Lokelma 10 g powder for oral suspension.
| Pharmaceutical Form |
|---|
|
Powder for oral suspension. White to grey powder. |
Lokelma 5 g powder for oral suspension:
Each sachet contains 5 g sodium zirconium cyclosilicate
Each 5 g sachet contains approximately 400 mg sodium.
Lokelma 10 g powder for oral suspension:
Each sachet contains 10 g sodium zirconium cyclosilicate
Each 10 g sachet contains approximately 800 mg sodium.
| Active Ingredient |
|---|
|
Sodium zirconium cyclosilicate is a non-absorbed, non-polymer inorganic powder with a uniform micropore structure that preferentially captures potassium in exchange for hydrogen and sodium cations. Sodium zirconium cyclosilicate captures potassium throughout the entire gastrointestinal (GI) tract and reduces the concentration of free potassium in the GI lumen, thereby lowering serum potassium levels and increasing faecal potassium excretion to resolve hyperkalaemia. |
| List of Excipients |
|---|
|
None. |
5 or 10 g of powder in sachets made of a PET/alu/LLDPE or PET/LDPE/alu/EAA/LLDPE laminate.
Pack sizes: 3 or 30 sachets.
Not all pack sizes may be marketed.
AstraZeneca AB, SE-151 85 Södertälje, Sweden
EU/1/17/1173/001
EU/1/17/1173/002
EU/1/17/1173/003
EU/1/17/1173/004
EU/1/17/1173/007
EU/1/17/1173/009
EU/1/17/1173/010
EU/1/17/1173/012
Date of first authorisation: 22 March 2018
Date of latest renewal: 15 February 2023
| Drug | Countries | |
|---|---|---|
| LOKELMA | Austria, Canada, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Italy, Japan, Lithuania, Netherlands, Poland, Romania, United Kingdom, United States |
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