Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2019 Publisher: Takeda UK Limited, Building 3, Glory Park, Glory Park Avenue, Wooburn Green, BUCKS, HP10 0DF
Matrifen, 12 micrograms/hour Transdermal patch.
Matrifen, 25 micrograms/hour Transdermal patch.
Matrifen, 50 micrograms/hour Transdermal patch.
Matrifen, 75 micrograms/hour Transdermal patch.
Matrifen, 100 micrograms/hour Transdermal patch.
| Pharmaceutical Form |
|---|
|
Transdermal patch. Rectangular, translucent patch on a removable protective film. The protective film is larger than the patch. Patches are marked with a coloured imprint stating the trade name and strength: Matrifen 12 micrograms/hour patch: brown imprint. |
Matrifen 12 micrograms/hour: Each transdermal patch contains 1.38 mg fentanyl in a patch of 4.2 cm² and releases fentanyl 12 micrograms/hour.
Matrifen 25 micrograms/hour: Each transdermal patch contains 2.75 mg fentanyl in a patch of 8.4 cm² and releases fentanyl 25 micrograms/hour.
Matrifen 50 micrograms/hour: Each transdermal patch contains 5.50 mg fentanyl in a patch of 16.8 cm² and releases fentanyl 50 micrograms/hour.
Matrifen 75 micrograms/hour: Each transdermal patch contains 8.25 mg fentanyl in a patch of 25.2 cm² and releases fentanyl 75 micrograms/hour.
Matrifen 100 micrograms/hour: Each transdermal patch contains 11.0 mg fentanyl in a patch of 33.6 cm² and releases fentanyl 100 micrograms/hour.
For the full list of excipients, see section 6.1.
| Active Ingredient | Description | |
|---|---|---|
| Fentanyl |
Fentanyl is a potent µ-opioid analgesic with rapid onset of analgesia and short duration of action. Its primary therapeutic actions are analgesia and sedation and is approximately 100-fold more potent than morphine as an analgesic. Secondary effects of fentanyl on central nervous system (CNS), respiratory and gastro-intestinal function are typical of opioid analgesics and are considered to be class effects. |
| List of Excipients |
|---|
|
Dipropylene glycol |
Each patch is packed in a heat-sealed sachet made of paper, aluminium and acrylonitrile-methyl acrylate-butadiene (AMAB) or made of paper, aluminium, polyethylene terephthalate (PET), polyethylene (PE) and cyclic olefin copolymer (LAS Pol A).
Pack sizes: 1, 2, 3, 4, 5, 8, 10, 16, and 20 patches.
Not all pack sizes may be marketed.
Takeda UK Limited, Building 3, Glory Park, Glory Park Avenue, Wooburn Green, BUCKS, HP10 0DF
12 microgram/hour: PL 16189/0014
25 microgram/hour: PL 16189/0015
50 microgram/hour: PL 16189/0016
75 microgram/hour: PL 16189/0017
100 microgram/hour: PL 16189/0018
16.09.2005 / 16.09.2010
| Drug | Countries | |
|---|---|---|
| MATRIFEN | Austria, Cyprus, Germany, Estonia, Spain, Finland, France, Ireland, Lithuania, Malta, Poland, United Kingdom |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.
