Fentanyl Other names: Fentanil Fentanyl citrate Phentanyl

Chemical formula: C₂₂H₂₈N₂O  Molecular mass: 336.471 g/mol  PubChem compound: 3345

Active ingredient description

Fentanyl is a potent µ-opioid analgesic with rapid onset of analgesia and short duration of action. Its primary therapeutic actions are analgesia and sedation and is approximately 100-fold more potent than morphine as an analgesic. Secondary effects of fentanyl on central nervous system (CNS), respiratory and gastro-intestinal function are typical of opioid analgesics and are considered to be class effects.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N01AH01 Fentanyl N Nervous system → N01 Anesthetics → N01A Anesthetics, general → N01AH Opioid anesthetics
Discover more medicines within N01AH01
N02AB03 Fentanyl N Nervous system → N02 Analgesics → N02A Opioids → N02AB Phenylpiperidine derivatives
Discover more medicines within N02AB03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MATRIFEN Transdermal patch Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
FENTORA Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
PECFENT Nasal spray, solution European Medicines Agency (EU) MPI, EU: SmPC
ABSTRAL Sublingual tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
FENTANYL Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 437-38-7
CAS Substance: 990-73-8
DrugBank Drug: DB00813
KEGG Drug: D00320
PubChem Compound: 3345
RxNorm Ingredient: 4337
SNOMED-CT Concept: 29190006
Fentanyl citrate (substance)
SNOMED-CT Concept: 373492002
Fentanyl (substance)
UNII Identifier: MUN5LYG46H
UNII Identifier: UF599785JZ


Fentanyl is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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