Fentanyl Other names: Fentanil Fentanyl citrate Phentanyl
Chemical formula: C₂₂H₂₈N₂O Molecular mass: 336.471 g/mol PubChem compound: 3345
Active ingredient description
Fentanyl is a potent µ-opioid analgesic with rapid onset of analgesia and short duration of action. Its primary therapeutic actions are analgesia and sedation and is approximately 100-fold more potent than morphine as an analgesic. Secondary effects of fentanyl on central nervous system (CNS), respiratory and gastro-intestinal function are typical of opioid analgesics and are considered to be class effects.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| N01AH01 | Fentanyl | N Nervous system → N01 Anesthetics → N01A Anesthetics, general → N01AH Opioid anesthetics |
| N02AB03 | Fentanyl | N Nervous system → N02 Analgesics → N02A Opioids → N02AB Phenylpiperidine derivatives |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| FENTANYL Solution for injection | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| PECFENT Nasal spray, solution | MPI, EU: SmPC | European Medicines Agency (EU) | |
| ABSTRAL Sublingual tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| MATRIFEN Transdermal patch | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| FENTORA Tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) |
Structural formula
3D molecular structure
External identifiers
- CAS Substance: 437-38-7
- CAS Substance: 990-73-8
- DrugBank Drug: DB00813
- KEGG Drug: D00320
- PubChem Compound: 3345
- RxNorm Ingredient: 4337
- SNOMED-CT Concept: 29190006
- Fentanyl citrate (substance)
- SNOMED-CT Concept: 373492002
- Fentanyl (substance)
- UNII Identifier: MUN5LYG46H
- FENTANYL CITRATE
- UNII Identifier: UF599785JZ
- FENTANYL
Medicines
Fentanyl is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)
Croatia (HR)
Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)Hong Kong (HK)Ireland (IE)
Israel (IL)
Italy (IT)Japan (JP)
Lithuania (LT)
Malta (MT)Mexico (MX)Netherlands (NL)
New Zealand (NZ)Poland (PL)
Romania (RO)Singapore (SG)South Africa (ZA)Spain (ES)
Tunisia (TN)Turkey (TR)United Kingdom (UK)
United States (US)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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