MEDODERMONE Cream Ref.[28226] Active ingredients: Clobetasol propionate

Source: Υπουργείο Υγείας (CY)  Revision Year: 2020  Publisher: MEDOCHEMIE LTD, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

Product name and form

Medodermone 0.05% w/w cream.

Pharmaceutical Form

Cream.

White, soft, homogeneous, smooth, odourless cream.

Qualitative and quantitative composition

Each 1 g of cream contains 0.5mg clobetasol propionate.

Excipients with known effect: cetostearyl alcohol, methyl-p-hydroxybenzoate and propyl-p-hydroxybenzoate.

For the full list of excipients, see section 6.1.

Active Ingredient Description
Clobetasol propionate

Clobetasol propionate, like other topical corticosteroids, has anti-inflammatory, antipruritic, and vasoconstrictive properties. Corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid.

List of Excipients

Liquid paraffin
Cetostearyl alcohol
White soft paraffin
Cetomacrogol 1000
Methyl-p-hydroxybenzoate (E218)
Propyl-p-hydroxybenzoate (E216)
Purified water

Pack sizes and marketing

PVC screwed-cap pilferproof aluminium tubes of 15 g and 25 g.

Not all pack sizes may be marketed.

Marketing authorization holder

MEDOCHEMIE LTD, 1-10 Constantinoupoleos street, 3011 Limassol, Cyprus

Marketing authorization dates and numbers

19980

Date of first authorization: 20/12/2005
Date of latest renewal: 24/05/2017

Drugs

Drug Countries
MEDODERMONE Cyprus, Hong Kong, Singapore

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