Source: FDA, National Drug Code (US) Revision Year: 2025
NUZOLVENCE for oral suspension contains zoliflodacin, an oral spiropyrimidinetrione bacterial type II topoisomerase inhibitor. The chemical name of zoliflodacin is (2R,4S,4aS)-11-Fluoro-1,2,4,4a-tetrahydro-2,4-dimethyl-8-[(4S)-4-methyl-2-oxo-3-oxazolidinyl]spiro[isoxazolo[4,5-g][1,4]oxazino[4,3-a]quinoline-5(6H),5′(2′H)-pyrimidine]-2′,4′,6′(1′H,3′H)-trione. Its molecular formula is C22H22FN5O7 and molecular mass is 487.4 g/mol. Its chemical structure is depicted below.
Each unit dose packet of NUZOLVENCE for oral suspension contains 3 g of zoliflodacin and the following inactive ingredients: colloidal silicon dioxide, croscarmellose sodium, magnesium stearate, mannitol, microcrystalline cellulose, talc, and xanthan gum.
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For Oral Suspension: 3 g of zoliflodacin as white to off-white granules in each unit-dose packet of NUZOLVENCE. |
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NUZOLVENCE (zoliflodacin) for oral suspension is supplied as a kit. Table 6. NUZOLVENCE Kit Configuration:
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| Drug | Countries | |
|---|---|---|
| NUZOLVENCE | United States |
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