PREDNISOLONE Suspension for injection Ref.[7046] Active ingredients: Prednisolone

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2017  Publisher: Amdipharm UK Limited, Capital House, 85 King William Street, London, EC4N 7BL, United Kingdom

Pharmacodynamic properties

Pharmacotherapeutic group: Glucocorticoids
ATC code: H02AB

Prednisolone is a glucocorticoid which has anti-inflammatory activity.

Pharmacokinetic properties

Absorption

Absorption following intramuscular injection is relatively slow. Systemic absorption occurs slowly after local, intra-articular injection.

Distribution

Prednisolone is extensively bound to plasma proteins.

Elimination

Excretion takes place via the urine as free and conjugated metabolites, together with an appreciable proportion of unchanged prednisolone.

Preclinical safety data

There is no pre-clinical data of relevance to a prescriber which is additional to that already included in other sections of the SmPC.

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