PREDNISOLONE Suppositories Ref.[7048] Active ingredients: Prednisolone

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2017  Publisher: RPH Pharmaceuticals AB, Lagervรคgen 7, 136 50 Jordbro, Sweden

Pharmacodynamic properties

ATC: A07EA01

Prednisolone sodium phosphate is an active corticosteroid with topical anti-inflammatory activity.

Pharmacokinetic properties

Biotransformation

Corticosteroids are metabolised mainly in the liver but also in the kidney and are excreted in the urine.

Synthetic corticosteroids such as prednisolone have increased potency when compared with the natural corticosteroids, due to their slower metabolism and lower protein-binding affinity.

Preclinical safety data

None stated.

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