Source: FDA, National Drug Code (US) Revision Year: 2020
RINVOQ is formulated with upadacitinib, a JAK inhibitor.
Upadacitinib has the following chemical name: (3S,4R)-3-Ethyl-4-(3Himidazo[1,2a]pyrrolo[2,3-e]pyrazin-8-yl)N(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide hydrate (2:1).
The strength of upadacitinib is based on anhydrous upadacitinib. The solubility of upadacitinib in water is 38 to less than 0.2 mg/mL across a pH range of 2 to 9 at 37 oC.
Upadacitinib has a molecular weight of 389.38 g/mol and a molecular formula of C17H19F3N6O • ½ H2O.
The chemical structure of upadacitinib is:
RINVOQ 15 mg extended-release tablets for oral administration are purple, biconvex oblong, with dimensions of 14 × 8 mm, and debossed with ‘a15’ on one side.
Each tablet contains the following inactive ingredients: microcrystalline cellulose, hypromellose, mannitol, tartaric acid, colloidal silicon dioxide, magnesium stearate, polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide, ferrosoferric oxide, and iron oxide red.
| Dosage Forms and Strengths |
|---|
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RINVOQ 15 mg extended-release tablets for oral administration are purple, biconvex oblong, with dimensions of 14 × 8 mm, and debossed with ‘a15’ on one side. |
| How Supplied |
|---|
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RINVOQ 15 mg extended-release tablets for oral administration are purple, biconvex oblong, with dimensions of 14 × 8 mm, and debossed with ‘a15’ on one side. 30 tablets in a bottle; NDC: 0074-2306-30 |
| Drug | Countries | |
|---|---|---|
| RINVOQ | Austria, Australia, Brazil, Canada, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Italy, Japan, Lithuania, Netherlands, New Zealand, Poland, Romania, Turkey, United Kingdom, United States, South Africa |
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