Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2020 Publisher: Norgine Pharmaceuticals Limited, Norgine House, Widewater Place, Moorhall Road, Harefield, Uxbridge, UB9 6NS, UK
Sinthrome Tablets 1mg.
| Pharmaceutical Form |
|---|
|
Tablets for oral administration. White, round, flat tablets with slightly bevelled edges, with one side bearing the imprint “CG”, and the other the imprint “AA”. |
Acenocoumarol BP 1mg.
Excipient(s) with known effect: Lactose (20 mg).
For the full list of excipients, see Section 6.1.
| Active Ingredient |
|---|
|
Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S. |
| List of Excipients |
|---|
|
Aerosil 200 (silica aerogel) |
Blister packs of 100 tablets.
Norgine Pharmaceuticals Limited, Norgine House, Widewater Place, Moorhall Road, Harefield, Uxbridge, UB9 6NS, UK
PL 20011/0068
Date of first authorisation: 08 August 1972
Date of latest renewal: 25 February 2005
| Drug | Countries | |
|---|---|---|
| SINTHROME | United Kingdom |
© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.