Chemical formula: C₁₉H₁₅NO₆  Molecular mass: 353.326 g/mol  PubChem compound: 54676537

Active ingredient description

Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B01AA07 Acenocoumarol B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AA Vitamin K antagonists
Discover more medicines within B01AA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SINTHROME Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 152-72-7
DrugBank Drug: DB01418
KEGG Drug: D07064
PubChem Compound: 54676537
RxNorm Ingredient: 154
SNOMED-CT Concept: 387457003
Acenocoumarol (substance)
UNII Identifier: I6WP63U32H


Acenocoumarol is an active ingredient of these brands:

Austria (AT)

France (FR)

Mexico (MX)

Poland (PL)

Romania (RO)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.