Acenocoumarol

Chemical formula: C₁₉H₁₅NO₆  Molecular mass: 353.326 g/mol  PubChem compound: 54676537

Active ingredient description

Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
B01AA07 Acenocoumarol B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AA Vitamin K antagonists
Discover more medicines within B01AA07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 SINTHROME Tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 152-72-7
DrugBank Drug: DB01418
KEGG Drug: D07064
PubChem Compound: 54676537
RxNorm Ingredient: 154
SNOMED-CT Concept: 387457003
Acenocoumarol (substance)
UNII Identifier: I6WP63U32H
ACENOCOUMAROL

Medicines

Acenocoumarol is an active ingredient of these brands:

Austria (AT)

France (FR)

Mexico (MX)

Poland (PL)

Romania (RO)

Spain (ES)

Tunisia (TN)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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