Acenocoumarol

Active ingredient description

Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Acenocoumarol
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AA Vitamin K antagonists
Discover more medicines within B01AA07

Medicines

Acenocoumarol is the active ingredient of these drugs:

Drug
Countries

France

United Kingdom

Austria France Poland Spain Tunisia

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Molecular mass: 353.326 g/mol

External identifiers

CAS Substance: 152-72-7
DrugBank Drug: DB01418
KEGG Drug: D07064
RxNorm Ingredient: 154
SNOMED-CT Concept: 387457003
Acenocoumarol (substance)
UNII Identifier: I6WP63U32H
ACENOCOUMAROL