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Acenocoumarol

Description

Acenocoumarol is a derivative of coumarin used as anticoagulant because acts as an antagonist of vitamin K. Vitamin K antagonists produce their anticoagulant effect by inhibition of the vitamin K-epoxide-reductase with a subsequent reduction of the gammacarboxylation of certain glutamic acid molecules which are located at several sites near the terminal end both of coagulation factors II (prothrombin), VII, IX, and X and of protein C or its cofactor protein S.

ATC Classification

Code
Title
Category
B01AA07
Acenocoumarol
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AA Vitamin K antagonists

Trade names

Trade name
Countries

France

United Kingdom

Austria France Spain

Product Monographs

Monograph
Type
Country
SINTHROME Tablet
MPI, EU: SmPC
UK