Acenocoumarol C₁₉H₁₅NO₆

Therapeutic indications

Acenocoumarol is indicated for:

Treatment and prevention of thromboembolic diseases

Population group: both men and women, only adults (18 years old or older)

Treatment and prevention of thromboembolic diseases.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Acenocoumarol is contraindicated in the following cases:

Heparin, platelet-aggregation inhibitors, pyrazolone derivatives and NSAIDs

at least one of
Heparin group
Heparin
Heparin
Heparin
Heparin
Platelet aggregation inhibitors excl. heparin
Diflunisal
Phenylbutazone
Pyrazolone derivatives
Non steroidal anti-inflammatory drugs (NSAIDS)
Methylprednisolone

Pregnancy

Pregnancy

Lactation

Lactation

Patients unable to co-operate

at least one of
Mental and behavioural disorders
Alcoholism (disorder)

Surgery on the central nervous system or eyes and traumatising surgery

Surgical and dental procedures

Peptic ulceration

Gastrointestinal ulcer

Haemorrhage

Bleeding

Acute pericarditis, pericardial effusion, infective endocarditis

at least one of
Acute pericarditis
Pericarditis in diseases classified elsewhere
Other diseases of pericardium
Acute and subacute endocarditis
Endocarditis, valve unspecified
Endocarditis and heart valve disorders in diseases classified elsewhere

Threatened abortion

Threatened abortion

Severe hypertension

Severe hepatic disease

Hepatic failure stage IV

Severe renal disease

at least one of

Cases of increased fibrinolytic activity

Fibrinolytic bleeding syndrome (disorder)

Acute pancreatitis

Acute pancreatitis

Vitamin K deficiency

Deficiency of vitamin K

Cranberry juice

Grapefruit

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2020: SINTHROME Tablet
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