Source: Medicines & Healthcare Products Regulatory Agency (GB) Revision Year: 2020 Publisher: GlaxoSmithKline UK Limited, 980 Great West Road, Brentford, Middlesex, TW8 9GS Trading as Stiefel
Toctino 10 mg capsules, soft.
Toctino 30 mg capsules, soft.
| Pharmaceutical Form |
|---|
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Capsule, soft. The Toctino 10 mg capsule is a brown oval capsule approximately 11 mm in length and 7 mm in width marked with “A1”. The Toctino 30 mg capsule is a red-brown oval capsule approximately 13 mm in length and 8 mm in width marked with “A3”. |
Each capsule, soft contains 10 mg or 30 mg of alitretinoin.
Excipients with known effect:
Soya-bean oil.
Each 10 mg capsule contains 176.50 mg soya-bean oil.
Each 30 mg capsule contains 282.40 mg soya-bean oil.
Sorbitol.
Each 10 mg capsule contains 20.08 mg sorbitol.
Each 30 mg capsule contains 25.66 mg sorbitol.
For the full list of excipients, see section 6.1.
| Active Ingredient |
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Alitretinoin is a naturally-occurring endogenous hormone related to vitamin A, binds to and activates all known intracellular retinoid receptor subtypes (RAR, RAR, RAR, RXR, RXR, RXR). The efficacy of alitretinoin in treating KS lesions may be related to the demonstrated ability of alitretinoin to inhibit the in vitro growth of KS cells. |
| List of Excipients |
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Capsule content: Soya-bean oil, refined Capsule shell: Gelatin |
PVC/PE/PVDC/Aluminum blisters. Pack sizes of 30 capsules, soft.
GlaxoSmithKline UK Limited, 980 Great West Road, Brentford, Middlesex, TW8 9GS
Trading as Stiefel
10mg, 30 capsules PL 19494/0252
30mg, 30 capsules PL 19494/0253
Date of first authorisation: 31 May 2013
Date of latest renewal: 30 July 2013
| Drug | Countries | |
|---|---|---|
| TOCTINO | Austria, Canada, Estonia, Spain, Finland, France, Israel, Netherlands, Poland, United Kingdom |
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