Alitretinoin Other names: 9-cis-retinoic acid Alitretinoin

Chemical formula: C₂₀H₂₈O₂  Molecular mass: 300.435 g/mol  PubChem compound: 449171

Active ingredient description

Alitretinoin is a naturally-occurring endogenous hormone related to vitamin A, binds to and activates all known intracellular retinoid receptor subtypes (RAR, RAR, RAR, RXR, RXR, RXR). The efficacy of alitretinoin in treating KS lesions may be related to the demonstrated ability of alitretinoin to inhibit the in vitro growth of KS cells.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
D11AH04 Alitretinoin D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AH Agents for dermatitis, excluding corticosteroids
Discover more medicines within D11AH04
L01XF02 Alitretinoin L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XF Retinoids for cancer treatment
Discover more medicines within L01XF02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 PANRETIN Gel MPI, EU: SmPC European Medicines Agency (EU)
 TOCTINO Capsule, soft MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 5300-03-8
DrugBank Drug: DB00523
KEGG Drug: D02815
PubChem Compound: 449171
RxNorm Ingredient: 81864
SNOMED-CT Concept: 116086005
Alitretinoin (substance)
UNII Identifier: 1UA8E65KDZ
ALITRETINOIN

Medicines

Alitretinoin is an active ingredient of these brands:

Austria (AT)

Canada (CA)

Estonia (EE)

Finland (FI)

France (FR)

Israel (IL)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Spain (ES)

United Kingdom (UK)

United States (US)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
Next: Usage >

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.

⇈