Alitretinoin C₂₀H₂₈O₂
Also known as: 9-cis-retinoic acid Alitretinoin

Active ingredient description

Alitretinoin is a naturally-occurring endogenous hormone related to vitamin A, binds to and activates all known intracellular retinoid receptor subtypes (RAR, RAR, RAR, RXR, RXR, RXR). The efficacy of alitretinoin in treating KS lesions may be related to the demonstrated ability of alitretinoin to inhibit the in vitro growth of KS cells.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
D11AH04
Alitretinoin
D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AH Agents for dermatitis, excluding corticosteroids
Discover more medicines within D11AH04
L01XF02
Alitretinoin
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XF Retinoids for cancer treatment
Discover more medicines within L01XF02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
PANRETIN Gel
European Medicines Agency (EU)
Summary of Product Characteristics (SPC)
TOCTINO Capsule, soft
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₀H₂₈O₂
Molecular mass: 300.435 g/mol

External identifiers

CAS Substance: 5300-03-8
DrugBank Drug: DB00523
KEGG Drug: D02815
PubChem Compound: 449171
RxNorm Ingredient: 81864
SNOMED-CT Concept: 116086005
Alitretinoin (substance)
UNII Identifier: 1UA8E65KDZ
ALITRETINOIN

Medicines

Alitretinoin is an active ingredient of these brands:

United States (US)

Austria (AT)

Canada (CA)

Estonia (EE)

Finland (FI)

France (FR)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Spain (ES)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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