Alitretinoin

Also known as: Alitretinoin 9-cis-retinoic acid

Active ingredient description

Alitretinoin is a naturally-occurring endogenous hormone related to vitamin A, binds to and activates all known intracellular retinoid receptor subtypes (RAR, RAR, RAR, RXR, RXR, RXR). The efficacy of alitretinoin in treating KS lesions may be related to the demonstrated ability of alitretinoin to inhibit the in vitro growth of KS cells.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
D11AH04
Alitretinoin
D Dermatologicals → D11 Other dermatological preparations → D11A Other dermatological preparations → D11AH Agents for dermatitis, excluding corticosteroids
Discover more medicines within D11AH04
L01XF02
Alitretinoin
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XF Retinoids for cancer treatment
Discover more medicines within L01XF02

Medicines

Alitretinoin is the active ingredient of these drugs:

Drug
Countries
ALITRETAN

Austria

ALIZEM

France Netherlands

PANRETIN

Estonia Lithuania Poland United States

TOCTINO

Austria Canada Estonia Finland France

ZEMATANE

New Zealand

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
PANRETIN Gel
Summary of Product Characteristics (SPC)
TOCTINO Capsule, soft
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

1UA8E65KDZ - ALITRETINOIN

CAS registry number

5300-03-8 - alitretinoin

SNOMED-CT

116086005 - Alitretinoin (substance)

 
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