TUZULBY Prolonged-release chewable tablet Ref.[115980] Active ingredients: Methylphenidate

Source: European Medicines Agency (EU)  Revision Year: 2025  Publisher: Neuraxpharm Pharmaceuticals, S.L., Avda. Barcelona 69, 08970 Sant Joan Despí - Barcelona, Spain

Product name and form

Tuzulby 20 mg prolonged-release chewable tablets.

Tuzulby 30 mg prolonged-release chewable tablets.

Tuzulby 40 mg prolonged-release chewable tablets.

Pharmaceutical Form

Prolonged-release chewable tablet.

Tuzulby 20 mg prolonged-release chewable tablets are speckled, off white, 6.8 x 14.7 mm capsule shaped coated tablet, debossed with "N2" "N2" on one side and bisect on the other side. The chewable tablet can be divided into equal doses.

Tuzulby 30 mg prolonged-release chewable tablets are speckled, off white, 7.7 x 16.8 mm capsule shaped coated tablet, debossed with "N3" "N3" on one side and bisect on the other side. The chewable tablet can be divided into equal doses.

Tuzulby 40 mg prolonged-release chewable tablets are speckled, off white, 8.5 x 18.5 mm capsule shaped coated tablet, debossed with "NP14" on one side and plain on the other side.

Qualitative and quantitative composition

Tuzulby 20 mg prolonged-release chewable tablets

Each tablet contains 20 mg methylphenidate hydrochloride equivalent to 17.30 mg of methylphenidate.

Excipient with known effect: Each tablet contains 6.1 mg aspartame (E951).

Tuzulby 30 mg prolonged-release chewable tablets

Each tablet contains 30 mg methylphenidate hydrochloride equivalent to 25.95 mg of methylphenidate.

Excipient with known effect: Each tablet contains 9.15 mg aspartame (E951).

Tuzulby 40 mg prolonged-release chewable tablets

Each tablet contains 40 mg methylphenidate hydrochloride equivalent to 34.59 mg of methylphenidate.

Excipient with known effect: Each tablet contains 12.2 mg aspartame (E951).

For the full list of excipients, see section 6.1.

Active Ingredient

Methylphenidate HCl is a mild central nervous system (CNS) stimulant. The mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD) is not known. Methylphenidate is thought to block the reuptake of noradrenaline and dopamine into the presynaptic neurone and increase the release of these monoamines into the extraneuronal space.

List of Excipients

Sodium polystyrene sulfonate
Povidone (E1201)
Triacetin (E1518)
Polyvinyl acetate
Sodium lauryl sulfate
Mannitol (E421)
Xanthan gum (E415)
Crospovidone (E1202)
Microcrystalline cellulose (E460)
Guar gum (E412)
Aspartame (E951)
Citric acid
Cherry flavour
Talc (E553b)
Silica colloidal hydrated
Magnesium stearate
Polyvinyl alcohol
Macrogol
Polysorbate 80 (E433)

Pack sizes and marketing

Pack size: 30 prolonged-release chewable tablets in a 60 mL HDPE bottle including a 2 g desiccant canister with a child-resistant cap (PP).

Marketing authorization holder

Neuraxpharm Pharmaceuticals, S.L., Avda. Barcelona 69, 08970 Sant Joan Despí - Barcelona, Spain

Marketing authorization dates and numbers

EU/1/24/1907/001 (20 mg x 30 prolonged-release chewable tablets)
EU/1/24/1907/002 (30 mg x 30 prolonged-release chewable tablets)
EU/1/24/1907/003 (40 mg x 30 prolonged-release chewable tablets)

Date of first authorisation: 28.02.2025

Drugs

Drug Countries
TUZULBY Austria, Estonia, France, Italy, Lithuania

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