Methylphenidate

Chemical formula: C₁₄H₁₉NO₂  Molecular mass: 233.306 g/mol  PubChem compound: 4158

Active ingredient description

Methylphenidate HCl is a mild central nervous system (CNS) stimulant. The mode of therapeutic action in Attention Deficit Hyperactivity Disorder (ADHD) is not known. Methylphenidate is thought to block the reuptake of noradrenaline and dopamine into the presynaptic neurone and increase the release of these monoamines into the extraneuronal space.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N06BA04 Methylphenidate N Nervous system → N06 Psychoanaleptics → N06B Psychostimulants, agents used for ADHD and nootropics → N06BA Centrally acting sympathomimetics
Discover more medicines within N06BA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CONCERTA Extended-release tablet Medicines and Medical Devices Safety Authority (NZ) MPI, EU: SmPC
MATORIDE XR Prolonged-release tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
RITALIN Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 113-45-1
CAS Substance: 298-59-9
DrugBank Drug: DB00422
KEGG Drug: D04999
PubChem Compound: 4158
RxNorm Ingredient: 6901
SNOMED-CT Concept: 373337007
Methylphenidate (substance)
UNII Identifier: 207ZZ9QZ49
METHYLPHENIDATE

Medicines

Methylphenidate is an active ingredient of these brands:

United States (US)

Australia (AU)

  • ARTIGE as METHYLPHENIDATE HYDROCHLORIDE
  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Austria (AT)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Brazil (BR)

  • ATTENZE as METHYLPHENIDATE HYDROCHLORIDE
  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDATO as METHYLPHENIDATE HYDROCHLORIDE
  • RITALINA as METHYLPHENIDATE HYDROCHLORIDE
  • TEDEAGA as METHYLPHENIDATE HYDROCHLORIDE

Canada (CA)

  • BIPHENTIN as METHYLPHENIDATE HYDROCHLORIDE
  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • FOQUEST as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Croatia (HR)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEFEDA as METHYLPHENIDATE HYDROCHLORIDE

Cyprus (CY)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

  • AFFENID as METHYLPHENIDATE HYDROCHLORIDE
  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE

Finland (FI)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE

France (FR)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • QUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • RITALINE as METHYLPHENIDATE HYDROCHLORIDE

Germany (DE)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • KINECTEEN as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • METHYSYM as METHYLPHENIDATE HYDROCHLORIDE
  • METIPHENAL as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Hong Kong (HK)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Ireland (IE)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Israel (IL)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • PHENIDIN as METHYLPHENIDATE HYDROCHLORIDE
  • REPHENIDATE as METHYLPHENIDATE HYDROCHLORIDE
  • RIAVENIR as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Japan (JP)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Lithuania (LT)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RUBIFEN as METHYLPHENIDATE HYDROCHLORIDE

Malta (MT)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE
  • RUBIFEN as METHYLPHENIDATE HYDROCHLORIDE
  • XAGGITIN as METHYLPHENIDATE HYDROCHLORIDE
  • XENIDATE as METHYLPHENIDATE HYDROCHLORIDE

Mexico (MX)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Netherlands (NL)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • KINECTEEN as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

New Zealand (NZ)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • DELMOSART as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE
  • RUBIFEN as METHYLPHENIDATE HYDROCHLORIDE

Nigeria (NG)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE

Poland (PL)

Romania (RO)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE

Singapore (SG)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE
  • RUBIFEN as METHYLPHENIDATE HYDROCHLORIDE

South Africa (ZA)

  • ADAPHEN as METHYLPHENIDATE HYDROCHLORIDE
  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • CONTRAMYL as METHYLPHENIDATE HYDROCHLORIDE
  • MEFEDINEL
  • NETALEX as METHYLPHENIDATE HYDROCHLORIDE
  • NEUCON as METHYLPHENIDATE HYDROCHLORIDE
  • RADD as METHYLPHENIDATE HYDROCHLORIDE
  • RALITIN as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE
  • RITAPHEN as METHYLPHENIDATE HYDROCHLORIDE

Spain (ES)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • DOPRILTEN as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • MEDICEBRAN as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RUBICRONO as METHYLPHENIDATE HYDROCHLORIDE
  • RUBIFEN as METHYLPHENIDATE HYDROCHLORIDE

Tunisia (TN)

  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

Turkey (TR)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • KONSENIDAT as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE

United Kingdom (UK)

  • CONCERTA as METHYLPHENIDATE HYDROCHLORIDE
  • DELMOSART as METHYLPHENIDATE HYDROCHLORIDE
  • EQUASYM as METHYLPHENIDATE HYDROCHLORIDE
  • MATORIDE as METHYLPHENIDATE HYDROCHLORIDE
  • MEDIKINET as METHYLPHENIDATE HYDROCHLORIDE
  • RITALIN as METHYLPHENIDATE HYDROCHLORIDE
  • TRANQUILYN as METHYLPHENIDATE HYDROCHLORIDE
  • XAGGITIN as METHYLPHENIDATE HYDROCHLORIDE
  • XENIDATE as METHYLPHENIDATE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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