ZOVIRAX Cream Ref.[6074] Active ingredients: Aciclovir

Source: Medicines & Healthcare Products Regulatory Agency (GB)  Revision Year: 2017  Publisher: The Wellcome Foundation Ltd, 980 Great West Road, Brentford, Middlesex, TW8 9GS, United Kingdom Trading as: GlaxoSmithKline UK, Stockley Park West, Uxbridge, Middlesex UB11 1BT

Therapeutic indications

Zovirax Cream is indicated for the treatment of Herpes Simplex virus infections of the skin including initial and recurrent genital herpes and herpes labialis.

Route of administration

Topical.

Do not use in eyes.

Posology and method of administration

Adults and Children

Zovirax Cream should be applied five times daily at approximately four hourly intervals, omitting the night time application.

Zovirax Cream should be applied to the lesions or impending lesions as soon as possible, preferably during the early stages (prodrome or erythema). Treatment can also be started during the later (papule or blister) stages.

Treatment should be continued for at least 4 days for herpes labialis and for 5 days for genital herpes. If healing has not occurred then treatment may be continued for up to an additional 5 days.

Use in the elderly

No special comment.

Overdose

No untoward effects would be expected if the entire contents of a 10 gram tube of Zovirax Cream containing 500 mg of aciclovir were ingested orally. However the accidental, repeated overdose of oral aciclovir, over several days has resulted in gastrointestinal effects (nausea and vomiting) and neurological effects (headache and confusion). Aciclovir is dialysable by haemodialysis.

Shelf life

Shelf life: 3 years.

Special precautions for storage

Store below 25°C. Do not refrigerate.

Nature and contents of container

Collapsible aluminium tubes with plastic screw caps.

Pack size: 2g or 10g tubes.

Special precautions for disposal and other handling

No special requirements.

Any unused medicinal product or waste material should be disposed of in accordance with local requirements.

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