Aciclovir Other names: Acyclovir

Chemical formula: C₈H₁₁N₅O₃  Molecular mass: 225.205 g/mol  PubChem compound: 135398513

Active ingredient description

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
D06BB03 Aciclovir D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06B Chemotherapeutics for topical use → D06BB Antivirals
Discover more medicines within D06BB03
J05AB01 Aciclovir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB01
S01AD03 Aciclovir S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AD Antivirals
Discover more medicines within S01AD03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ZOVIRAX Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZOVIRAX Dispersible film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Zovirax Eye Ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Zovirax Intravenous injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
SITAVIG Delayed-release tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 59277-89-3
DrugBank Drug: DB00787
KEGG Drug: D00222
PubChem Compound: 135398513
RxNorm Ingredient: 281
SNOMED-CT Concept: 372729009
Aciclovir (substance)
UNII Identifier: X4HES1O11F


Aciclovir is an active ingredient of these brands:

United States (US)

Albania (AL)

Australia (AU)

Canada (CA)

Cyprus (CY)

Estonia (EE)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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