Aciclovir C₈H₁₁N₅O₃
Also known as: Acyclovir

Active ingredient description

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
D06BB03
Aciclovir
D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06B Chemotherapeutics for topical use → D06BB Antivirals
Discover more medicines within D06BB03
J05AB01
Aciclovir
J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB01
S01AD03
Aciclovir
S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AD Antivirals
Discover more medicines within S01AD03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
Zovirax Intravenous injection
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)
Zovirax Eye Ointment
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)
ZOVIRAX Cream
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)
SITAVIG Delayed-release tablet
FDA, National Drug Code (US)
Structured Product Labeling (SPL/PLR)
ZOVIRAX Dispersible film-coated tablets
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₈H₁₁N₅O₃
Molecular mass: 225.205 g/mol

External identifiers

CAS Substance: 59277-89-3
DrugBank Drug: DB00787
KEGG Drug: D00222
PubChem Compound: 135398513
RxNorm Ingredient: 281
SNOMED-CT Concept: 372729009
Aciclovir (substance)
UNII Identifier: X4HES1O11F
ACYCLOVIR

Medicines

Aciclovir is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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