Aciclovir

Also known as: Acyclovir

Active ingredient description

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Aciclovir
D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06B Chemotherapeutics for topical use → D06BB Antivirals
Discover more medicines within D06BB03
Aciclovir
J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB01
Aciclovir
S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AD Antivirals
Discover more medicines within S01AD03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Summary of Product Characteristics (SPC)
UK
Structured Product Labeling (SPL/PLR)
US

Medicines

Aciclovir is the active ingredient of these drugs:

Drug
Countries

Romania

Italy

Austria

Germany

Brazil

Brazil

Austria Germany

Hong Kong

Hong Kong

South Africa

South Africa

Brazil

Estonia Germany

Poland

Finland

Hong Kong

Finland Hong Kong

Hong Kong

Austria France South Africa

Finland

Turkey

Hong Kong

Finland South Africa

Hong Kong

Ecuador Hong Kong

Hong Kong

Turkey

Ecuador

Hong Kong Singapore

Italy

Tunisia

Brazil

Turkey

Turkey

Turkey

Tunisia

South Africa

Hong Kong Singapore

Poland

Hong Kong

Singapore

South Africa

Mexico

Tunisia

Italy

Italy

Ecuador

Hong Kong

Brazil

Ecuador

South Africa

Hong Kong

Hong Kong

Cyprus Hong Kong

Italy

United Kingdom

Hong Kong

Ecuador

Hong Kong Singapore

Hong Kong

Ecuador

Hong Kong

Hong Kong

Ecuador

Brazil

Brazil

Hong Kong

Hong Kong

Poland

Brazil

Hong Kong

Hong Kong

Turkey

Turkey

Hong Kong

Singapore

France

Brazil

Turkey

Poland Tunisia

Romania

Ecuador

Finland

Brazil

Brazil

Poland

Poland

Brazil

Poland

Hong Kong

France

Turkey

Netherlands

Ecuador

Spain

Hong Kong

United Kingdom

Ecuador

Australia New Zealand Singapore

South Africa

Cyprus Estonia Hong Kong Singapore

Hong Kong

Tunisia

Hong Kong

Ecuador

Italy

Hong Kong

Hong Kong

Ecuador

Turkey

Hong Kong

Ecuador

Italy

France United States

Hong Kong

Cyprus Hong Kong

Hong Kong

Hong Kong

Hong Kong

Italy

Turkey

Tunisia

Singapore

Cyprus

Singapore

New Zealand

Ecuador Turkey

Ireland

Romania

United Kingdom

New Zealand

Singapore

Hong Kong Singapore

Romania

Hong Kong Singapore

Lithuania Romania

Austria

Ecuador

Turkey

Turkey

Hong Kong Singapore

Cyprus

Hong Kong Spain

Australia Germany Hong Kong New Zealand Poland

Hong Kong

Hong Kong

Germany

Hong Kong

Austria Cyprus Finland Germany Poland

Brazil

Hong Kong Singapore

Hong Kong Singapore

Hong Kong Singapore

Hong Kong

Hong Kong

Spain

Austria Brazil Canada Cyprus Ecuador

Hong Kong

Brazil

Aciclovir is also found within below combination drugs:

ACTIVIR DUO , HERPAZON , XERESE , ZOVIDUO , ZOVIRAX DUO

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₈H₁₁N₅O₃
Molecular mass: 225.205 g/mol

External identifiers

CAS Substance: 59277-89-3
DrugBank Drug: DB00787
KEGG Drug: D00222
PubChem Compound: 135398513
RxNorm Ingredient: 281
SNOMED-CT Concept: 372729009
Aciclovir (substance)
UNII Identifier: X4HES1O11F
ACYCLOVIR