ATC Group: D06BB Antivirals

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of D06BB in the ATC hierarchy

Level Code Title
1 D Dermatologicals
2 D06 Antibiotics and chemotherapeutics for dermatological use
3 D06B Chemotherapeutics for topical use
4 D06BB Antivirals

Group D06BB contents

Code Title
D06BB01 Idoxuridine
D06BB02 Tromantadine
D06BB03 Aciclovir
D06BB04 Podophyllotoxin
D06BB05 Inosine
D06BB06 Penciclovir
D06BB07 Lysozyme
D06BB08 Ibacitabine
D06BB09 Edoxudine
D06BB10 Imiquimod
D06BB11 Docosanol
D06BB12 Sinecatechins
D06BB53

Active ingredients in D06BB

Active Ingredient Description
Aciclovir

Acyclovir is an antiviral agent with activity against herpes simplex virus and varicella-zoster virus. Acyclovir inhibits the DNA polymerase of the virus, preventing further proliferation.

Docosanol

The exact mechanism of the antiviral activity of docosanol is unknown. In vitro studies indicate that docosanol affects the fusion between the virus and the plasma membrane, which inhibits intracellular uptake and replication of virus. Docosanol has no effect against non-enveloped viruses.

Imiquimod

Imiquimod is an immune response modifier. Saturable binding studies suggest a membrane receptor for imiquimod exists on responding immune cells. Imiquimod has no direct antiviral activity.

Lysozyme

Lysozyme is a naturally occurring enzyme found in bodily secretions such as tears, saliva, and milk. It functions as an antimicrobial agent by cleaving the peptidoglycan component of bacterial cell walls, which leads to cell death.

Penciclovir

Penciclovir has demonstrated in vivo and in vitro activity against herpes simplex viruses (types 1 and 2) and varicella zoster virus. Penciclovir triphosphate persists in infected cells for more than 12 hours where it inhibits replication of viral DNA and has a half-life of 9, 10 and 20 hours in cells infected with varicella zoster virus, herpes simplex virus type 1 and herpes simplex virus type 2 respectively.

Podophyllotoxin

Podophyllotoxin is a metaphase inhibitor in dividing cells binding to at least one binding site on tubulin. Binding prevents tubulin polymerisation required for microtubule assembly. At higher concentrations, podophyllotoxin also inhibits nucleoside transport through the cell membrane.

Sinecatechins
Tromantadine

Tromantadine is an antiviral medicine used to treat herpes simplex virus.

Related product monographs

Title Information Source Document Type  
ALDARA Cream European Medicines Agency (EU) MPI, EU: SmPC
CONDYLINE Cutaneous solution Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CYCLOVAX Cream Υπουργείο Υγείας (CY) MPI, EU: SmPC
CYCLOVAX Tablet Υπουργείο Υγείας (CY) MPI, EU: SmPC
MEDOVIR Cream Υπουργείο Υγείας (CY) MPI, EU: SmPC
MEDOVIR Powder for solution for infusion Υπουργείο Υγείας (CY) MPI, EU: SmPC
MEDOVIR Tablet Υπουργείο Υγείας (CY) MPI, EU: SmPC
VECTAVIR Cream Health Products Regulatory Authority (IE) MPI, EU: SmPC
VEREGEN Ointment FDA, National Drug Code (US) MPI, US: SPL/PLR
WARTICON Topical cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZOVIRAX Cream Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZOVIRAX Dispersible film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Zovirax Eye Ointment Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Zovirax Intravenous injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
ZYCLARA Cream FDA, National Drug Code (US) MPI, US: SPL/PLR