Acamprosate
Chemical formula: C₅H₁₁NO₄S Molecular mass: 181.21 g/mol PubChem compound: 71158
Active ingredient description
Acamprosate has a chemical structure similar to that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier. Acamprosate may act by stimulating GABAergic inhibitory neurotransmission and antagonising excitatory aminoacids, particularly glutamate. It is indicated as therapy to maintain abstinence in alcohol-dependent patients.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC Group | Classification | |
|---|---|---|
| N07BB03 | Acamprosate | N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BB Drugs used in alcohol dependence |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Document | Type | Information Source | |
|---|---|---|---|
| CAMPRAL Enterocoated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) |
Medicines
Acamprosate is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Canada (CA)
Estonia (EE)
France (FR)
Ireland (IE)
Japan (JP)
Netherlands (NL)
Poland (PL)
South Africa (ZA)
Spain (ES)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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