Acamprosate

Active ingredient description

Acamprosate has a chemical structure similar to that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier. Acamprosate may act by stimulating GABAergic inhibitory neurotransmission and antagonising excitatory aminoacids, particularly glutamate. It is indicated as therapy to maintain abstinence in alcohol-dependent patients.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
N07BB03
Acamprosate
N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BB Drugs used in alcohol dependence
Discover more medicines within N07BB03

Medicines

Acamprosate is the active ingredient of these drugs:

Drug
Countries
AOTAL

France

BESOBRIAL

South Africa

CAMPRAL

Australia Austria Canada Estonia Ireland

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
CAMPRAL Enterocoated tablet
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

N4K14YGM3J - ACAMPROSATE

CAS registry number

77337-76-9 - acamprosate

SNOMED-CT

391698009 - Acamprosate (substance)

 
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