ATC Group: N07BB Drugs used in alcohol dependence

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N07BB in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N07 Other nervous system drugs
3 N07B Drugs used in addictive disorders
4 N07BB Drugs used in alcohol dependence

Group N07BB contents

Code Title
N07BB01 Disulfiram
N07BB02 Calcium carbimide
N07BB03 Acamprosate
N07BB04 Naltrexone
N07BB05
N07BB06

Active ingredients in N07BB

Active Ingredient

Acamprosate has a chemical structure similar to that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier. Acamprosate may act by stimulating GABAergic inhibitory neurotransmission and antagonising excitatory aminoacids, particularly glutamate. It is indicated as therapy to maintain abstinence in alcohol-dependent patients.

Disulfiram is an inhibitor of numerous enzymes. Disulfiram is used to support the treatment of chronic alcoholism.

Nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile. Nalmefene is indicated for the reduction of alcohol consumption in adult patients with alcohol dependence, without physical withdrawal symptoms and who do not require immediate detoxification.

Naltrexone is an orally used, long acting specific opioid antagonist. Naltrexone binds competitively to receptors which are located in the central and peripheral nervous system and hence blocks the access for exogenously administered opioids.

Related product monographs

Document Type Information Source  
 ADEPEND Film-coated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 ANTABUSE Tablet MPI, US: SPL/Old FDA, National Drug Code (US)
 CAMPRAL Enterocoated tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
 ESPERAL Tablets MPI, EU: SmPC
 ETHYLEX Film-coated tablet MPI, EU: SmPC Health Products Regulatory Authority (IE)
 REVIA Tablet MPI, CA: SPM Health Products and Food Branch (CA)
 SELINCRO Film-coated tablet MPI, EU: SmPC European Medicines Agency (EU)