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ATC Group: N07BB Drugs used in alcohol dependence

Anatomical Therapeutic Chemical Classification System

Hierarchical Position

Level
Code
Title
1
N
Nervous system
2
N07
Other nervous system drugs
3
N07B
Drugs used in addictive disorders
4
N07BB
Drugs used in alcohol dependence

Contents

Code
Title
N07BB01
Disulfiram
N07BB02
Calcium carbimide
N07BB03
Acamprosate
N07BB04
Naltrexone
N07BB05
Nalmefene

Active Ingredients

Chemical substance
Description
Acamprosate

Acamprosate has a chemical structure similar to that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier. It is indicated as therapy to maintain abstinence in alcohol-dependent patients.

Disulfiram

Disulfiram is an inhibitor of numerous enzymes. Disulfiram is used to support the treatment of chronic alcoholism.

Nalmefene

Nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile. Nalmefene is indicated for the reduction of alcohol consumption in adult patients with alcohol dependence, without physical withdrawal symptoms and who do not require immediate detoxification.

Naltrexone

Naltrexone is an orally used, long acting specific opioid antagonist. Naltrexone binds competitively to receptors which are located in the central and peripheral nervous system and hence blocks the access for exogenously administered opioids.

Monographs

Monograph
Type
Country
ANTABUSE Tablet
MPI, US: SPL/Old
US
CAMPRAL Enterocoated tablet
MPI, EU: SmPC
UK
ESPERAL Tablets
MPI, EU: SmPC
PT
SELINCRO Film-coated tablet
MPI, EU: SmPC