ATC Group: N07BB Drugs used in alcohol dependence
Anatomical Therapeutic Chemical Classification System
Acamprosate has a chemical structure similar to that of amino acid neuromediators, such as taurine or gamma-amino-butyric acid (GABA), including an acetylation to permit passage across the blood brain barrier. It is indicated as therapy to maintain abstinence in alcohol-dependent patients.
Disulfiram is an inhibitor of numerous enzymes. Disulfiram is used to support the treatment of chronic alcoholism.
Nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile. Nalmefene is indicated for the reduction of alcohol consumption in adult patients with alcohol dependence, without physical withdrawal symptoms and who do not require immediate detoxification.