Nalmefene

Chemical formula: C₂₁H₂₅NO₃  Molecular mass: 339.435 g/mol 

Active ingredient description

Nalmefene is an opioid system modulator with a distinct μ, δ, and κ receptor profile. Nalmefene is indicated for the reduction of alcohol consumption in adult patients with alcohol dependence, without physical withdrawal symptoms and who do not require immediate detoxification.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07BB05 N Nervous system → N07 Other nervous system drugs → N07B Drugs used in addictive disorders → N07BB Drugs used in alcohol dependence
Discover more medicines within N07BB05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
SELINCRO Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 55096-26-9
DrugBank Drug: DB06230
KEGG Drug: D05111
RxNorm Ingredient: 31479
SNOMED-CT Concept: 109098006
Nalmefene (substance)
UNII Identifier: TOV02TDP9I
NALMEFENE

Medicines

Nalmefene is an active ingredient of these brands:

Austria (AT)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Israel (IL)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

Poland (PL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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