Acetohydroxamic acid

Chemical formula: C₂H₅NO₂  Molecular mass: 75.067 g/mol  PubChem compound: 1990

Active ingredient description

Acetohydroxamic acid (AHA) is a stable, synthetic compound derived from hydroxylamine and ethyl acetate. Its molecular structure is similar to urea. AHA reversibly inhibits the bacterial enzyme urease, thereby inhibiting the hydrolysis of urea and production of ammonia in urine infected with urea-splitting organisms. The reduced ammonia levels and decreased pH enhance the effectiveness of antimicrobial agents and allow an increased cure rate of these infections.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
G04BX03 Acetohydroxamic acid G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BX Other urologicals
Discover more medicines within G04BX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
LITHOSTAT Tablet FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 546-88-3
DrugBank Drug: DB00551
KEGG Drug: D00220
PubChem Compound: 1990
RxNorm Ingredient: 16728
SNOMED-CT Concept: 387426003
Acetohydroxamic acid (substance)
UNII Identifier: 4RZ82L2GY5


Acetohydroxamic acid is an active ingredient of these brands:

United States (US)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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