Acetohydroxamic acid

Active ingredient description

Acetohydroxamic acid (AHA) is a stable, synthetic compound derived from hydroxylamine and ethyl acetate. Its molecular structure is similar to urea. AHA reversibly inhibits the bacterial enzyme urease, thereby inhibiting the hydrolysis of urea and production of ammonia in urine infected with urea-splitting organisms. The reduced ammonia levels and decreased pH enhance the effectiveness of antimicrobial agents and allow an increased cure rate of these infections.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Acetohydroxamic acid
G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BX Other urologicals
Discover more medicines within G04BX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Structured Product Labeling (SPL)
US

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂H₅NO₂
Molecular mass: 75.067 g/mol

External identifiers

CAS Substance: 546-88-3
DrugBank Drug: DB00551
KEGG Drug: D00220
PubChem Compound: 1990
RxNorm Ingredient: 16728
SNOMED-CT Concept: 387426003
Acetohydroxamic acid (substance)
UNII Identifier: 4RZ82L2GY5
ACETOHYDROXAMIC ACID

Medicines

Acetohydroxamic acid is an active ingredient of these brands:

United States (US)

Spain (ES)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.