Acitretin
Active ingredient description
Acitretin, a synthetic aromatic derivative of retinoic acid, has a favourable therapeutic ratio, with a greater and more specific inhibitory effect on psoriasis and disorders of epithelial keratinisation. The usual therapeutic response to acitretin consists of desquamation (with or without erythema) followed by more normal re-epithelialisation. Acitretin is the main active metabolite of etretinate.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
Medicines
Acitretin is the active ingredient of these drugs:
Poland
Austria
Australia Brazil Estonia Finland Hong Kong
Australia
New Zealand Singapore
Turkey
Canada France United States
Hong Kong
Australia
Italy
Structural formula
Chemical formula: C₂₁H₂₆O₃
Molecular mass: 326.429 g/mol