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Acitretin

Description

Acitretin, a synthetic aromatic derivative of retinoic acid, has a favourable therapeutic ratio, with a greater and more specific inhibitory effect on psoriasis and disorders of epithelial keratinisation. The usual therapeutic response to acitretin consists of desquamation (with or without erythema) followed by more normal re-epithelialisation. Acitretin is the main active metabolite of etretinate.

ATC Classification

Code
Title
Category
D05BB02
Acitretin
D Dermatologicals → D05 Antipsoriatics → D05B Antipsoriatics for systemic use → D05BB Retinoids for treatment of psoriasis

Trade names

Trade name
Countries
KERACUTAN

Austria

NEOTIGASON

Australia Netherlands Singapore Spain United Kingdom

NOVATIN

Australia

NOVATRETIN

Singapore

SORIATANE

Canada France United States

ZETIN

Australia

Product Monographs

Monograph
Type
Country
ACITRETIN Capsule, hard
MPI, EU: SmPC
UK
SORIATANE Capsule
MPI, US: SPL/Old
US

2D Molecule Structure

Unique Ingredient Identifier (UNII)

LCH760E9T7 - ACITRETIN

CAS Registry Number

55079-83-9 - acitretin

SNOMED-CT

386938006 - Acitretin (substance)

 
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