Acitretin

Chemical formula: C₂₁H₂₆O₃ Molecular mass: 326.429 g/mol PubChem compound: 5284513

Therapeutic indications

Acitretin is indicated for:

Cornification disorders

Population group: only adults (18 years old or older)

Acitretin is indicated for:

Severe extensive psoriasis which is resistant to other forms of therapy.
Palmo-plantar pustular psoriasis.
Severe congenital ichthyosis.
Severe Darier’s disease (keratosis follicularis).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

25mg or 30mg for 2 to 4 weeks

Contraindications

Acitretin is contraindicated in the following cases:

Pregnancy and lactation

Pregnancy

Breastfeeding

Lactation

Severe hepatic impairment

Hepatic failure stage IV

Severe renal impairment

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Tetracyclines

Μethotrexate

Methotrexate

Vitamin A, retinoids

at least one of

Vitamin A
Retinoids for topical use in acne
Retinoids for treatment of acne
Retinoids for treatment of psoriasis

Alcohol

Progesterone

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