Adapalene
Active ingredient description
Adapalene is a retinoid-like compound which in, in vivo and in vitro models of inflammation, has been demonstrated to possess anti-inflammatory properties. Mechanically, adapalene binds like tretinoin to specific retinoic acid nuclear receptors but, unlike tretinoin not to cytosolic receptor binding proteins. Adapalene is used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
Medicines
Adapalene is the active ingredient of these drugs:
Poland
Tunisia
Hong Kong
Brazil
Cyprus
Brazil
Brazil
Brazil
South Africa
Brazil South Africa
Singapore
Austria Brazil Canada Estonia Finland
France Lithuania Spain Tunisia
Hong Kong
Hong Kong
Hong Kong
Hong Kong
Hong Kong
South Africa
Hong Kong
Adapalene is also found within below combination drugs:
ADACNE CLIN , DERIVA C , EFFEZEL , EPIDUO , TACTUPUMP
Product monographs
Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):
Structural formula
3D molecular structure
Unique ingredient identifier (UNII)
1L4806J2QF - ADAPALENE
CAS registry number
106685-40-9 - adapalene
SNOMED-CT
332377001 - Adapalene (substance)
386934008 - Adapalene (substance)