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Adapalene

Description

Adapalene is a retinoid-like compound which in, in vivo and in vitro models of inflammation, has been demonstrated to possess anti-inflammatory properties. Mechanically, adapalene binds like tretinoin to specific retinoic acid nuclear receptors but, unlike tretinoin not to cytosolic receptor binding proteins. Adapalene is used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions.

ATC Classification

Code
Title
Category
D10AD03
Adapalene
D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AD Retinoids for topical use in acne

Trade names

Trade name
Countries

Cyprus

Singapore

Austria Canada Netherlands Singapore United Kingdom

France Spain

Trade names (in combination): EFFEZEL EPIDUO TACTUPUMP

Product Monographs

Monograph
Type
Country
DIFFERIN Cream
MPI, EU: SmPC
UK