Adapalene

Description

Adapalene is a retinoid-like compound which in, in vivo and in vitro models of inflammation, has been demonstrated to possess anti-inflammatory properties. Mechanically, adapalene binds like tretinoin to specific retinoic acid nuclear receptors but, unlike tretinoin not to cytosolic receptor binding proteins. Adapalene is used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions.

Medicine classification

ATC Code
Title
Class
D10AD03
Adapalene
D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AD Retinoids for topical use in acne

Medicines

Drug
Countries
ACURE

Hong Kong

ADAFERIN

Cyprus

DIFACLEAR

Singapore

DIFFERIN

Austria Canada Hong Kong Lithuania Netherlands

DIFFERINE

France Lithuania Spain

DIPALEN

Hong Kong

ELLIA

Hong Kong

FONA

Hong Kong

KLENZIT MS

Hong Kong

NIFFULENE

Hong Kong

TIFFORLY

Hong Kong

Other medications with this active ingredient in combination: EFFEZEL EPIDUO TACTUPUMP

Product monographs

Monograph
Type
Country
DIFFERIN Cream
MPI, EU: SmPC
UK

2D Molecule Structure

2D representation of molecule

3D Molecule Structure

3D representation of molecule

Unique Ingredient Identifier (UNII)

1L4806J2QF - ADAPALENE

CAS Registry Number

106685-40-9 - adapalene

SNOMED-CT

386934008 - Adapalene (substance)

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