Adapalene

Description

Adapalene is a retinoid-like compound which in, in vivo and in vitro models of inflammation, has been demonstrated to possess anti-inflammatory properties. Mechanically, adapalene binds like tretinoin to specific retinoic acid nuclear receptors but, unlike tretinoin not to cytosolic receptor binding proteins. Adapalene is used in the treatment of acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions.

Medicine classification

ATC Code
Title
Class
Adapalene
D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AD Retinoids for topical use in acne

Medicines

Drug
Countries

Hong Kong

Cyprus

Singapore

Austria Canada Hong Kong Lithuania Netherlands

France Lithuania Spain

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Other medications with this active ingredient in combination: EFFEZEL EPIDUO TACTUPUMP

Product monographs

Monograph
Type
Country
MPI, EU: SmPC
UK

2D Molecule Structure

2D representation of molecule

3D Molecule Structure

3D representation of molecule

Unique Ingredient Identifier (UNII)

1L4806J2QF - ADAPALENE

CAS Registry Number

106685-40-9 - adapalene

SNOMED-CT

386934008 - Adapalene (substance)