Adefovir dipivoxil

Chemical formula: C₈H₁₂N₅O₄P  Molecular mass: 501.471 g/mol  PubChem compound: 60871

Therapeutic indications

Adefovir dipivoxil is indicated for:

Chronic hepatitis B

Population group: only adults (18 - 65 years old)

Adefovir dipivoxil is indicated for the treatment of chronic hepatitis B in adults with:

  • compensated liver disease with evidence of active viral replication, persistently elevated serum alanine aminotransferase (ALT) levels and histological evidence of active liver inflammation and fibrosis. Initiation of adefovir dipivoxil treatment should only be considered when the use of an alternative antiviral agent with a higher genetic barrier to resistance is not available or appropriate.
  • decompensated liver disease in combination with a second agent without cross-resistance to adefovir dipivoxil.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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