Alendronic acid Other names: Alendronate sodium

Chemical formula: C₄H₁₃NO₇P₂  Molecular mass: 249.096 g/mol  PubChem compound: 2088

Active ingredient description

Alendronic acid is a bisphosphonate that inhibits osteoclastic bone resorption with no direct effect on bone formation. The bone formed during treatment with alendronic acid is of normal quality.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
M05BA04 Alendronic acid M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BA Bisphosphonates
Discover more medicines within M05BA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 FOSAMAX Once Weekly Tablets MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 121268-17-5
CAS Substance: 66376-36-1
DrugBank Drug: DB00630
PubChem Compound: 2088
RxNorm Ingredient: 236083
SNOMED-CT Concept: 391730008
Alendronic acid (substance)
UNII Identifier: X1J18R4W8P
ALENDRONIC ACID

Medicines

Alendronic acid is an active ingredient of these brands:

Albania (AL)

Australia (AU)

Austria (AT)

  • FOSAMAX as Alendronate sodium trihydrate
  • ONELY as Alendronate sodium trihydrate
  • OSTEONAT as ALENDRONATE SODIUM
  • (combination) ADROVANCE as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate
  • (combination) VANTAVO

Brazil (BR)

Canada (CA)

  • FOSAMAX as Alendronate sodium trihydrate
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Croatia (HR)

  • ALENDOR as ALENDRONATE SODIUM
  • FOROSA as Alendronate sodium trihydrate
  • FOSAMAX as Alendronate sodium trihydrate
  • (combination) ADROVANCE as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate
  • (combination) VANTAVO

Cyprus (CY)

  • BINOSTO as Alendronate sodium trihydrate
  • LEDRONIN as Alendronate sodium trihydrate
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • BINOSTO as Alendronate sodium trihydrate
  • (combination) FOSASTAD as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

France (FR)

  • BONASOL as Alendronate sodium trihydrate
  • FOSAMAX as Alendronate sodium trihydrate
  • STEOVESS as ALENDRONATE SODIUM
  • (combination) ADROVANCE as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Germany (DE)

  • BINOSTO as Alendronate sodium trihydrate
  • FOSAMAX as Alendronate sodium trihydrate
  • TEVANATE as Alendronate sodium monohydrate
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Hong Kong (HK)

Ireland (IE)

Israel (IL)

  • BINOSTO as Alendronate sodium trihydrate
  • FOSALAN as ALENDRONATE SODIUM
  • MAXIBONE as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

  • CALIDRON as ALENDRONATE SODIUM
  • FOSALEN as Alendronate sodium trihydrate
  • (combination) FOSALEN D3 as ALENDRONATE SODIUM
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

Turkey (TR)

United Kingdom (UK)

  • BINOSTO as Alendronate sodium trihydrate
  • FOSAMAX as Alendronate sodium trihydrate
  • (combination) BENTEXO
  • (combination) FOSAVANCE as Alendronate sodium trihydrate

United States (US)

  • BINOSTO as Alendronate sodium trihydrate
  • FOSAMAX as Alendronate sodium trihydrate
  • (combination) FOSAMAX PLUS as ALENDRONATE SODIUM

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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