Alendronic acid

Also known as: Alendronate sodium

Active ingredient description

Alendronic acid is a bisphosphonate that inhibits osteoclastic bone resorption with no direct effect on bone formation. The bone formed during treatment with alendronic acid is of normal quality.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Alendronic acid
M Musculo-skeletal system → M05 Drugs for treatment of bone diseases → M05B Drugs affecting bone structure and mineralization → M05BA Bisphosphonates
Discover more medicines within M05BA04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Medicines

Alendronic acid is the active ingredient of these drugs:

Drug
Countries

Spain

Turkey

Romania

South Africa

Hong Kong

Turkey

Brazil

Hong Kong

Poland

New Zealand

Hong Kong

Poland

Italy

Ecuador

Italy

Estonia

Hong Kong South Africa

Turkey

Ecuador

Italy

Hong Kong

Cyprus Estonia Finland Germany Ireland

Turkey

Brazil

Brazil

France Ireland Netherlands

Turkey

Turkey

Brazil

Turkey

South Africa

Tunisia

Australia South Africa

Italy

Ecuador

Brazil

Ecuador

South Africa

Australia

Turkey

South Africa

Tunisia

Austria Brazil Canada France Germany

Turkey

South Africa

Ireland

Italy

South Africa

Italy

Brazil

Cyprus

Turkey

Singapore

Estonia

Ecuador

Italy

Brazil

Hong Kong

South Africa

Italy

Italy

Austria

South Africa

Ecuador

Brazil

Lithuania Poland

South Africa

Brazil

Poland

South Africa

Brazil

Brazil

Hong Kong

Turkey

Ecuador

Austria

South Africa

Ecuador

Poland

South Africa

Brazil

Ecuador

Italy

Italy

Hong Kong

South Africa

Estonia Poland

Spain

Spain

Estonia France

Romania

Estonia Germany Hong Kong Ireland

Turkey

Alendronic acid is also found within below combination drugs:

ADROVANCE , ALEFORT , ALENCALCI D3 , ALENDIL D , BENTEXO , BONENDRO , BONENORM , BONEX-D , BONMEGA , BONYL , BONYL PLUS , DA-BONE , FONATPLUS , FOSALEN D3 , FOSAMAX D , FOSAMAX PLUS , FOSASTAD , FOSAVANCE , OSSOFORTIN A , OSTEOCAL , OSTEOMIX PLUS , OSTEONATE PLUS , OSTEOPLUS D , OSVIPAC , TEBONEVA , TRIDEPOS , VANTAVO , VEGABON PLUS D

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₄H₁₃NO₇P₂
Molecular mass: 249.096 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 121268-17-5
CAS Substance: 66376-36-1
DrugBank Drug: DB00630
PubChem Compound: 2088
RxNorm Ingredient: 236083
SNOMED-CT Concept: 391730008
Alendronic acid (substance)
UNII Identifier: X1J18R4W8P
ALENDRONIC ACID