Alendronic acid Other names: Alendronate sodium

Chemical formula: C₄H₁₃NO₇P₂ Molecular mass: 249.096 g/mol PubChem compound: 2088

Therapeutic indications

Alendronic acid is indicated for:

Osteoporosis

Population group: only adults (18 years old or older)

Alendronic acid is indicated for the treatment of:

osteoporosis in post-menopausal women to prevent fractures
osteoporosis in men to prevent fractures
glucocorticoid-induced osteoporosis and prevention of bone loss in post-menopausal women considered at risk of developing the disease

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Alendronic acid is contraindicated in the following cases:

Hypocalcaemia

Hypocalcemia

Pregnancy

Delay of oesophageal emptying such as stricture or achalasia

at least one of

Stricture of esophagus
Achalasia of esophagus

Inability to stand or sit upright for at least 30 minutes

Unable to stand up

Renal impairment where creatinine clearance is less than 35 ml/min

at least one of

Renal failure stage 5: Kidney failure (GFR <15 mL/min/1.73 m2 or dialysis)

Breast-feeding

Lactation

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